Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.87 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3896275 | 0.93 | POLB (1.00) | POLBMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL19675345 | 0.90 | POLB (0.71) | POLBMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL19116323 | 0.90 | POLB (0.71) | POLBMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL8378911 | 0.90 | POLB (0.71) | POLBMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL12293627 | 0.90 | POLB (0.71) | POLBMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL7292108 | 0.90 | POLB (0.71) | POLBMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL7298052 | 0.85 | POLB (0.65) | POLBMEN1KMT2AMAPTNPC1 | |
| SCHEMBL19116476 | 0.85 | POLB (0.65) | POLBMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL16242699 | 0.85 | POLB (0.77) | POLBMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL16242574 | 0.83 | POLB (0.68) | POLBMEN1KMT2AMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140348880-A1 | Ortho-Aminothiophenol Compounds and Uses Thereof | UNIV CAPE BRETON (CA) | 2014-11-27 | — | — | US | disclosed |
| US-20140348880-A1 | Ortho-Aminothiophenol Compounds and Uses Thereof | UNIV CAPE BRETON (CA) | 2014-11-27 | — | — | US | disclosed |
| US-20140348880-A1 | Ortho-Aminothiophenol Compounds and Uses Thereof | UNIV CAPE BRETON (CA) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140348880-A1 | Ortho-Aminothiophenol Compounds and Uses Thereof | TPMT, ALPI, CYP4F2 | POLB 2983/4885MEN1 3361/4885KMT2A 1458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.