Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CD44 | P16070 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11385640 | 0.73 | MAPT (0.46) | MAPTTDP1KMT2ANPSR1CYP3A4 | |
| SCHEMBL1014289 | 0.71 | MAPT (0.54) | MAPTTDP1KMT2ANPSR1CYP3A4 | |
| SCHEMBL540557 | 0.71 | MAPT (0.54) | MAPTTDP1KMT2ANPSR1CYP3A4 | |
| SCHEMBL16602223 | 0.70 | MAPT (0.73) | MAPTTDP1KMT2ANPSR1CYP3A4 | |
| SCHEMBL3859717 | 0.70 | CYP3A4 (0.52) | MAPTTDP1KMT2ANPSR1CYP3A4 | |
| Hydrochloric Acid SCHEMBL19896479 | 0.70 | MAPT (0.52) | MAPTTDP1KMT2ANPSR1CYP3A4 | |
| SCHEMBL17879583 | 0.69 | MAPT (0.46) | MAPTTDP1KMT2ANPSR1CYP3A4 | |
| SCHEMBL28598261 | 0.69 | ESR1 (0.50) | MAPTTDP1NPSR1CYP3A4ESR1 | |
| SCHEMBL17879577 | 0.68 | MAPT (0.50) | MAPTTDP1KMT2ANPSR1CYP3A4 | |
| SCHEMBL9018894 | 0.67 | MAPT (0.54) | MAPTTDP1KMT2ANPSR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140348880-A1 | Ortho-Aminothiophenol Compounds and Uses Thereof | UNIV CAPE BRETON (CA) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140348880-A1 | Ortho-Aminothiophenol Compounds and Uses Thereof | TPMT, ALPI, CYP4F2 | MAPT 1076/4885TDP1 2738/4885KMT2A 1458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.