Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 4/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.33 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.32 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.32 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.32 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2107555 | 0.90 | P2RY2 (0.36) | P2RY2P2RY14TDP1P2RY4 | |
| SCHEMBL15892157 | 0.89 | P2RY14 (0.36) | P2RY2P2RY14TDP1P2RY4 | |
| SCHEMBL15841304 | 0.89 | P2RY14 (0.36) | P2RY2P2RY14TDP1P2RY4 | |
| SCHEMBL15850593 | 0.89 | P2RY14 (0.36) | P2RY2P2RY14TDP1P2RY4 | |
| SCHEMBL18902444 | 0.89 | P2RY14 (0.36) | P2RY2P2RY14TDP1P2RY4 | |
| SCHEMBL17853308 | 0.89 | P2RY14 (0.36) | P2RY2P2RY14TDP1P2RY4 | |
| SCHEMBL16243030 | 0.88 | SLC28A1 (0.33) | P2RY2P2RY14TDP1P2RY4SLC28A1 | |
| SCHEMBL25134191 | 0.87 | SLC28A1 (0.33) | P2RY2P2RY14TDP1P2RY4SLC28A1 | |
| SCHEMBL12114737 | 0.87 | SLC28A1 (0.33) | P2RY2P2RY14TDP1P2RY4SLC28A1 | |
| SCHEMBL1318144 | 0.87 | SLC28A1 (0.33) | P2RY2P2RY14TDP1P2RY4SLC28A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140350080-A1 | INHIBITION OF VIRAL GENE EXPRESSION | UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG (ZA) | 2014-11-27 | — | — | US | disclosed |