SCHEMBL16243746

SCHEMBL16243746

CC=CC(=O)OCCC/C(=C\C(=O)O)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 6/20 0.45
ATM Q13315 1/20 0.42
TSHR P16473 3/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HPGD P15428 1/20 0.33
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
GSTP1 P09211 1/20 0.31
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5436641 1.00 HCAR2 (0.45) HCAR2ATMTSHRKDM4EMAPT
SCHEMBL20164944 0.90 HCAR2 (0.42) HCAR2ATMTSHRKDM4EGSTP1
SCHEMBL29405120 0.83 HCAR2 (0.65) HCAR2ATMTSHRMAPTRAB9A
Butyl Fumarate SCHEMBL30853660 0.80 HCAR2 (0.71) HCAR2ATMTSHRMAPTRAB9A
Butyl Fumarate SCHEMBL31207800 0.80 HCAR2 (0.71) HCAR2ATMTSHRMAPTRAB9A
SCHEMBL29774224 0.79 ATM (0.58) HCAR2ATMTSHRMAPTRAB9A
SCHEMBL6365129 0.79 ATM (0.50) HCAR2ATMTSHRMAPTRAB9A
Stearyl Fumaric Acid SCHEMBL29801553 0.78 HCAR2 (0.72) HCAR2ATMTSHRKDM4EMAPT
SCHEMBL30853661 0.78 HCAR2 (0.72) HCAR2ATMTSHRKDM4EMAPT
SCHEMBL30853650 0.78 HCAR2 (0.72) HCAR2ATMTSHRKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9177819-B2 Method for manufacturing silicon substrate having textured structure TOKUYAMA CORPORATION (JP) 2015-11-03 US disclosed
US-20140349485-A1 METHOD FOR MANUFACTURING SILICON SUBSTRATE HAVING TEXTURED STRUCTURE TOKUYAMA CORPORATION a corporation 2014-11-27 US disclosed