Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Butyric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 3/20 | 0.93 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.93 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.93 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.93 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.93 |
| ▸ | CA1 | P00915 | 3/20 | 0.60 |
| ▸ | CES2 | O00748 | 2/20 | 0.59 |
| ▸ | CES1 | P23141 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | FABP3 | P05413 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyric Acid SCHEMBL5571749 | 0.93 | FFAR3 (0.93) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL11814057 | 0.93 | FFAR3 (0.93) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL10908702 | 0.93 | FFAR3 (0.93) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL11441641 | 0.93 | FFAR3 (0.93) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL1330878 | 0.93 | — | — | |
| Butyric Acid SCHEMBL9800297 | 0.93 | FFAR3 (0.93) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL2587931 | 0.93 | FFAR3 (0.93) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL11419652 | 0.93 | FFAR3 (0.93) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL4292004 | 0.93 | FFAR3 (1.00) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL601096 | 0.93 | FFAR3 (0.93) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2416756-A2 | STABLE PHARMACEUTICAL COMPOSITIONS WITH HIGH BIOAVAILIBILITY | Bilgic, Mahmut (TR) | 2012-02-15 | — | — | EP | claimed |
| WO-2010117346-A2 | STABLE PHARMACEUTICAL COMPOSITIONS WITH HIGH BIOAVAILIBILITY | BILGIC MAHMUT (TR) | 2010-10-14 | — | — | WO | claimed |
| WO-2007149815-A1 | STRONTIUM COMPOSITIONS AND METHODS OF TREATING ARTHRITIC AND OR OSTEOPORITIC CONDITIONS | THERAGENEX, LLC (US) | 2007-12-27 | — | — | WO | claimed |
| WO-2007149816-A2 | STRONTIUM COMPOSITIONS AND METHODS OF TREATING OSTEOPOROTIC CONDITIONS | THERAGENEX, LLC (US) | 2007-12-27 | — | — | WO | claimed |
| US-20070292535-A1 | Strontium compositions and methods of treating arthritic and or osteoporitic conditions | TRX PHARMACEUTICALS, LLC | 2007-12-20 | — | — | US | claimed |
| US-20070292529-A1 | Strontium compositions and methods of treating osteoporotic conditions | TRX PHARMACEUTICALS, LLC | 2007-12-20 | — | — | US | claimed |
| US-3943186-A | Method for producing isopentene | UBE INDUSTRIES, LTD. (JA) | 1976-03-09 | — | — | US | claimed |
| EP-3830315-B1 | HEAT TRANSFER FLUIDS CONTAINING SYNERGISTIC BLENDS OF CORROSION INHIBITOR FORMULATIONS | PRESTONE PRODUCTS CORP (US) | 2025-07-16 | — | — | EP | disclosed |
| EP-3484976-B1 | HEAT TRANSFER FLUIDS AND METHODS FOR PREVENTING CORROSION IN HEAT TRANSFER SYSTEMS | PRESTONE PRODUCTS CORP (US) | 2024-05-29 | — | — | EP | disclosed |
| CN-110366597-B | Blood profiling with protease inhibitors | 善威生物私人有限公司 | 2024-03-29 | — | — | CN | disclosed |
| US-20240060997-A1 | Blood Preparation and Profiling | SANGUI BIO PTY LTD (AU) | 2024-02-22 | — | — | US | disclosed |
| CN-112996951-B | Heat transfer fluids containing synergistic blends of corrosion inhibitor formulations | 布拉斯通产品公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-107250318-B | Super concentrate additive solution compositions | 布拉斯通产品公司 | 2023-10-27 | — | — | CN | disclosed |
| US-6508951-B1 | Low Phosphorus content, heat exchange systems for internal combustion engines; aliphatic dibasic acids, alkyl benzoic acids, strontium compounds, phosphoric acids and alkali metal phosphates; glycol; triazole or thiazole corrosion inhibitors | CCI KABUSHIKI KAISHA (JP) | 2003-01-21 | — | — | US | disclosed |
| EP-1149810-A1 | SANITARY EARTHEN PRODUCTS | TOTO LTD. (JP) | 2001-10-31 | — | — | EP | disclosed |
| EP-1081250-A1 | Low phosphorus coolant composition | CCI Kabushiki Kaisha (JP) | 2001-03-07 | — | — | EP | disclosed |
| US-5645634-A | Composition and method for forming Ba1-X Srx Tiy O3 thin films | MITSUBISHI MATERIALS CORPORATION (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0558311-A1 | Light-sensitive lithographic printing plate | KONICA CORPORATION (JP) | 1993-09-01 | — | — | EP | disclosed |
| US-4959347-A | SUPERCONDUCTORS | MITSUBISHI DENKI KABUSHIKI KAISHA (JP) | 1990-09-25 | — | — | US | disclosed |
| US-3943186-A | Method for producing isopentene | UBE INDUSTRIES, LTD. (JA) | 1976-03-09 | — | — | US | disclosed |