Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16248102 | 0.89 | BTK (0.56) | BTK | |
| SCHEMBL1724827 | 0.89 | BTK (0.70) | BTK | |
| SCHEMBL611518 | 0.89 | BTK (0.67) | BTK | |
| SCHEMBL1726635 | 0.80 | BTK (0.74) | BTK | |
| SCHEMBL13178675 | 0.79 | BTK (0.57) | BTK | |
| SCHEMBL1728409 | 0.78 | BTK (0.80) | BTK | |
| SCHEMBL611424 | 0.78 | BTK (0.66) | BTK | |
| SCHEMBL1728753 | 0.77 | BTK (0.78) | BTK | |
| SCHEMBL1726283 | 0.77 | BTK (0.74) | BTK | |
| SCHEMBL608965 | 0.76 | BTK (0.71) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603500-B1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | HOFFMANN LA ROCHE (CH) | 2014-11-19 | — | — | EP | disclosed |