Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL609595 | 0.89 | BTK (0.53) | BTK | |
| SCHEMBL10262808 | 0.83 | BTK (0.52) | BTK | |
| SCHEMBL16248113 | 0.82 | BTK (0.58) | BTK | |
| SCHEMBL13964669 | 0.81 | BTK (0.57) | BTK | |
| SCHEMBL611319 | 0.81 | BTK (0.57) | BTK | |
| SCHEMBL12503526 | 0.81 | BTK (0.57) | BTK | |
| Potassium Ion SCHEMBL626696 | 0.80 | BTK (0.57) | BTK | |
| SCHEMBL10201392 | 0.78 | BTK (0.40) | BTK | |
| SCHEMBL15029133 | 0.77 | BTK (0.53) | BTK | |
| SCHEMBL14914745 | 0.77 | BTK (0.50) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603500-B1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | HOFFMANN LA ROCHE (CH) | 2014-11-19 | — | — | EP | disclosed |