Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL609741 | 0.73 | CHEK1 (0.39) | BTK | |
| SCHEMBL18866534 | 0.72 | BTK (0.43) | BTK | |
| SCHEMBL14696416 | 0.71 | BTK (0.37) | BTK | |
| SCHEMBL19910951 | 0.66 | BTK (0.38) | BTK | |
| SCHEMBL1041157 | 0.66 | CYP19A1 (0.37) | — | |
| SCHEMBL31292107 | 0.63 | CA1 (0.41) | — | |
| SCHEMBL16013601 | 0.63 | — | — | |
| SCHEMBL31292221 | 0.63 | CYP19A1 (0.35) | — | |
| SCHEMBL1626865 | 0.63 | SCN10A (0.36) | — | |
| SCHEMBL27223739 | 0.63 | CYP19A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603500-B1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | HOFFMANN LA ROCHE (CH) | 2014-11-19 | — | — | EP | disclosed |