Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14914679 | 0.88 | BTK (0.80) | BTKKCNH2 | |
| SCHEMBL14696350 | 0.86 | BTK (0.67) | BTKKCNH2 | |
| SCHEMBL14914734 | 0.85 | BTK (0.70) | BTKKCNH2 | |
| SCHEMBL14696549 | 0.85 | BTK (0.67) | BTKKCNH2 | |
| SCHEMBL14929591 | 0.84 | BTK (0.70) | BTKKCNH2 | |
| SCHEMBL14696537 | 0.83 | BTK (0.69) | BTKKCNH2 | |
| SCHEMBL14696702 | 0.83 | BTK (0.67) | BTKKCNH2 | |
| SCHEMBL14915601 | 0.83 | BTK (0.85) | BTKKCNH2 | |
| SCHEMBL14696494 | 0.83 | BTK (0.68) | BTKKCNH2 | |
| SCHEMBL14929627 | 0.82 | BTK (0.61) | BTKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889682-B2 | Inhibitors of bruton'S tyrosine kinase | HOFFMANN-LA ROCHE INC. (US) | 2014-11-18 | — | — | US | disclosed |