⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21474778 | 1.00 | — | — | |
| SCHEMBL19577797 | 1.00 | — | — | |
| SCHEMBL19608817 | 0.89 | — | — | |
| SCHEMBL10005842 | 0.89 | — | — | |
| SCHEMBL1644129 | 0.89 | — | — | |
| SCHEMBL15964497 | 0.89 | — | — | |
| SCHEMBL19577789 | 0.89 | — | — | |
| SCHEMBL17754495 | 0.88 | — | — | |
| SCHEMBL19577793 | 0.88 | SSTR1 (0.30) | — | |
| SCHEMBL16248353 | 0.88 | SSTR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140343127-A1 | COMPOUNDS FOR THE MODULATION OF SMN2 SPLICING | Santaris Pharma A/S a corporation | 2014-11-20 | — | — | US | disclosed |