Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.85 |
| ▸ | KDR | P35968 | 2/20 | 0.85 |
| ▸ | PDE4A | P27815 | 1/20 | 0.85 |
| ▸ | BLVRB | P30043 | 1/20 | 0.85 |
| ▸ | HTT | P42858 | 1/20 | 0.85 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.74 |
| ▸ | THRB | P10828 | 2/20 | 0.74 |
| ▸ | RECQL | P46063 | 2/20 | 0.74 |
| ▸ | APP | P05067 | 1/20 | 0.74 |
| ▸ | BLM | P54132 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.64 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3386039 | 1.00 | MEN1 (0.85) | MEN1KMT2AKDRPDE4ABLVRB | |
| SCHEMBL1624756 | 0.92 | MEN1 (0.70) | MEN1KMT2AKDRPDE4ABLVRB | |
| Olsalazine SCHEMBL29861404 | 0.92 | MEN1 (1.00) | MEN1KMT2AKDRPDE4ABLVRB | |
| SCHEMBL26730466 | 0.92 | MEN1 (0.70) | MEN1KMT2AKDRPDE4ABLVRB | |
| Olsalazine SCHEMBL25118 | 0.92 | MEN1 (1.00) | MEN1KMT2AKDRPDE4ABLVRB | |
| SCHEMBL3385330 | 0.92 | MEN1 (0.70) | MEN1KMT2AKDRPDE4ABLVRB | |
| Olsalazine SCHEMBL25119 | 0.92 | MEN1 (1.00) | MEN1KMT2AKDRPDE4ABLVRB | |
| Olsalazine SCHEMBL29378994 | 0.92 | MEN1 (1.00) | MEN1KMT2AKDRPDE4ABLVRB | |
| Olsalazine SCHEMBL29385751 | 0.92 | MEN1 (1.00) | MEN1KMT2AKDRPDE4ABLVRB | |
| Olsalazine SCHEMBL2628413 | 0.92 | MEN1 (1.00) | MEN1KMT2AKDRPDE4ABLVRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1993517-B1 | MODIFIED RELEASE FORMULATIONS AND METHODS OF TREATING INFLAMMATORY BOWEL DISEASE | ALLERGAN PHARMACEUTICALS INT LTD (IE) | 2019-05-08 | — | — | EP | claimed |
| EP-1663253-B1 | FORMULATIONS CONTAINING SALICYLATES AND THEIR USE FOR TREATING INFLAMMATORY BOWEL DISEASE | AGI THERAPEUTICS RES LTD (IE) | 2010-12-01 | — | — | EP | claimed |
| US-7825106-B2 | Modified release formulations and methods of treating inflammatory bowel disease | AGI THERAPEUTICS LTD. (IE) | 2010-11-02 | — | — | US | claimed |
| US-7737133-B2 | Formulations and methods of treating inflammatory bowel disease | AGI THERAPEUTICS LTD. (IE) | 2010-06-15 | — | — | US | claimed |
| EP-1993517-A2 | MODIFIED RELEASE FORMULATIONS AND METHODS OF TREATING INFLAMMATORY BOWEL DISEASE | AGI Therapeutics Research Limited (IE) | 2008-11-26 | — | — | EP | claimed |
| WO-2007119177-A2 | MODIFIED RELEASE FORMULATIONS AND METHODS OF TREATING INFLAMMATORY BOWEL DISEASE | AGI THERAPEUTICS RESEARCH LIMITED (US) | 2007-10-25 | — | — | WO | claimed |
| US-20060223787-A1 | Modified release formulations and methods of treating inflammatory bowel disease | ALLERGAN PHARMACEUTICALS INTERNATIONAL LIMITED (IE) | 2006-10-05 | — | — | US | claimed |
| US-20050090473-A1 | Formulations and methods of treating inflammatory bowel disease | ALLERGAN PHARMACEUTICALS INTERNATIONAL LIMITED (IE) | 2005-04-28 | — | — | US | claimed |
| EP-0133423-B1 | USE OF 4,5'-AZO-BIS-SALICYLIC ACID FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF INFLAMMATORY DISORDERS IN THE INTESTINE | PHARMACIA AB (SE) | 1987-11-25 | — | — | EP | claimed |
| US-4591584-A | ANTIINFLAMMATORY AGENTS; GASTRO INTESTINAL DISORDERS | PHARMACIA AB (SE) | 1986-05-27 | — | — | US | claimed |
| EP-0145777-A1 | AZO-BIS-SALICYLIC ACID AND SALT THEREOF, PHARMACEUTICAL FORMULATIONS AND USES OF SAID ACID AND SALT, AND PRODUCTION OF THE ACID | PHARMACIA AB (SE) | 1985-06-26 | — | — | EP | claimed |
| EP-0133423-A1 | Use of 4,5'-azo-bis-salicylic acid for the manufacture of a medicament for the treatment of inflammatory disorders in the intestine | PHARMACIA AB (SE) | 1985-02-20 | — | — | EP | claimed |
| WO-1985000013-A1 | AZO-BIS-SALICYLIC ACID AND SALT THEREOF, PHARMACEUTICAL FORMULATIONS AND USES OF SAID ACID AND SALT, AND PRODUCTION OF THE ACID | PHARMACIA AB (SE) | 1985-01-03 | — | — | WO | claimed |
| EP-1993517-B1 | MODIFIED RELEASE FORMULATIONS AND METHODS OF TREATING INFLAMMATORY BOWEL DISEASE | ALLERGAN PHARMACEUTICALS INT LTD (IE) | 2019-05-08 | — | — | EP | disclosed |
| US-7928092-B2 | Formulations and methods of treating inflammatory bowel disease | AGI THERAPEUTICS LTD. (IE) | 2011-04-19 | — | — | US | disclosed |
| EP-1663253-B1 | FORMULATIONS CONTAINING SALICYLATES AND THEIR USE FOR TREATING INFLAMMATORY BOWEL DISEASE | AGI THERAPEUTICS RES LTD (IE) | 2010-12-01 | — | — | EP | disclosed |
| EP-0133423-A1 | Use of 4,5'-azo-bis-salicylic acid for the manufacture of a medicament for the treatment of inflammatory disorders in the intestine | PHARMACIA AB (SE) | 1985-02-20 | — | — | EP | disclosed |
| EP-0133423-A1 | Use of 4,5'-azo-bis-salicylic acid for the manufacture of a medicament for the treatment of inflammatory disorders in the intestine | PHARMACIA AB (SE) | 1985-02-20 | — | — | EP | disclosed |
| WO-1985000013-A1 | AZO-BIS-SALICYLIC ACID AND SALT THEREOF, PHARMACEUTICAL FORMULATIONS AND USES OF SAID ACID AND SALT, AND PRODUCTION OF THE ACID | PHARMACIA AB (SE) | 1985-01-03 | — | — | WO | disclosed |
| WO-1985000013-A1 | AZO-BIS-SALICYLIC ACID AND SALT THEREOF, PHARMACEUTICAL FORMULATIONS AND USES OF SAID ACID AND SALT, AND PRODUCTION OF THE ACID | PHARMACIA AB (SE) | 1985-01-03 | — | — | WO | disclosed |