SCHEMBL16249154

SCHEMBL16249154

Cc1ccc(-c2nnc(-c3ccccc3)n2-c2cccc3ccccc23)cc1

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47
MAPT P10636 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
HIF1A Q16665 1/20 0.46
AVPR1A P37288 1/20 0.45
AKT1 P31749 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12593290 0.97 AKT1 (0.46) THRBRXFP1MAPTAKT1
SCHEMBL29349692 0.92 SMN1; SMN2 (0.51) SMN1; SMN2HIF1AAKT1
SCHEMBL28949385 0.92 SMN1; SMN2 (0.51) SMN1; SMN2HIF1AAKT1
SCHEMBL44765 0.92 SMN1; SMN2 (0.51) SMN1; SMN2HIF1AAKT1
SCHEMBL19289688 0.89 TSHR (0.47) SMN1; SMN2HIF1AAKT1
SCHEMBL16241067 0.86 TSHR (0.49) RXFP1SMN1; SMN2HIF1AAKT1
SCHEMBL26230390 0.86 AVPR1A (0.56) AVPR1A
SCHEMBL13417867 0.84 AKT1 (0.47) AVPR1AAKT1
SCHEMBL766101 0.84 SMN1; SMN2 (0.43) SMN1; SMN2HIF1AAKT1
SCHEMBL16249161 0.84 AKT1 (0.54) SMN1; SMN2HIF1AAKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220399513-A1 ORGANIC PHOTODETECTOR AND ELECTRONIC DEVICE HAVING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2022-12-15 US disclosed
WO-2020024557-A1 ELECTRON TRANSPORT MATERIAL AND APPLICATION THEREOF 广东聚华印刷显示技术有限公司 2020-02-06 WO disclosed
US-9054320-B2 1, 2, 4-triazole-based derivative, production process and use thereof, and organic electroluminescent device BOE TECHNOLOGY GROUP CO., LTD. (CN) 2015-06-09 US disclosed
US-20140343293-A1 1, 2, 4-TRIAZOLE-BASED DERIVATIVE, PRODUCTION PROCESS AND USE THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE JiLin OLED Material Tech. Co., LTD. (CN) 2014-11-20 US disclosed