Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | SYK | P43405 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | TTBK1 | Q5TCY1 | 3/20 | 0.47 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 3/20 | 0.45 |
| ▸ | BRAF | P15056 | 3/20 | 0.45 |
| ▸ | RET | P07949 | 2/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1319475 | 0.88 | TP53 (0.71) | TP53MAPTHDAC6SYKGLA | |
| SCHEMBL657571 | 0.81 | TP53 (0.62) | TP53MAPTHDAC6SYKGLA | |
| SCHEMBL2389236 | 0.81 | MEN1 (0.56) | MAPTHTTEGFRABCG2 | |
| SCHEMBL7771269 | 0.79 | EGFR (0.66) | TP53MAPTHDAC6SYKGLA | |
| SCHEMBL21704805 | 0.77 | TP53 (1.00) | TP53MAPTHDAC6SYKCYP3A4 | |
| SCHEMBL658048 | 0.75 | SYK (0.60) | TP53MAPTHDAC6SYKGLA | |
| SCHEMBL1317961 | 0.73 | HDAC6 (1.00) | TP53MAPTHDAC6SYKGLA | |
| SCHEMBL1389429 | 0.72 | CYP3A4 (0.86) | MAPTHDAC6SYKGLAHTT | |
| SCHEMBL30026816 | 0.72 | CYP3A4 (0.86) | MAPTHDAC6SYKGLAHTT | |
| SCHEMBL12517646 | 0.72 | TNNI3K (0.85) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014183300-A1 | VEGFR TYROSINE KINASE INHIBITORS | SUZHOU VIVOTIDE BIOTECHNOLOGIES CO., LTD. (CN) | 2014-11-20 | — | — | WO | disclosed |