Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT1A1 | P22309 | 3/20 | 0.67 |
| ▸ | MLNR | O43193 | 1/20 | 0.67 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.67 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.67 |
| ▸ | CCKAR | P32238 | 1/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.67 |
| ▸ | GHSR | Q92847 | 1/20 | 0.67 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.67 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.67 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | CTSD | P07339 | 6/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6785 | 0.90 | UGT1A1 (0.81) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| Hydrochloric Acid SCHEMBL6668 | 0.90 | UGT1A1 (0.80) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL16250688 | 0.86 | UGT1A1 (0.77) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL12103069 | 0.86 | UGT1A1 (0.91) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL13315150 | 0.86 | UGT1A1 (0.74) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL12103173 | 0.84 | UGT1A1 (0.80) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL3553186 | 0.83 | UGT1A1 (0.56) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL3553181 | 0.83 | UGT1A1 (0.56) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL2436359 | 0.83 | CYP3A4 (0.60) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL8232164 | 0.83 | UGT1A1 (0.69) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140343290-A1 | PROCESS FOR THE PREPARATION OF ATAZANAVIR OR ITS BISULFATE SALT | RANBAXY LABORATORIES LIMITED (IN) | 2014-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140343290-A1 | PROCESS FOR THE PREPARATION OF ATAZANAVIR OR ITS BISULFATE SALT | DNPEP, NSUN2, JMJD7 | UGT1A1 1373/4885MLNR 3847/4885NR1I2 2588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.