Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 14/20 | 0.81 |
| ▸ | HTR2C | P28335 | 13/20 | 0.81 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.81 |
| ▸ | DRD2 | P14416 | 8/20 | 0.79 |
| ▸ | DRD4 | P21917 | 8/20 | 0.79 |
| ▸ | DRD3 | P35462 | 4/20 | 0.79 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.79 |
| ▸ | HTR1A | P08908 | 1/20 | 0.79 |
| ▸ | HTR7 | P34969 | 1/20 | 0.79 |
| ▸ | HTR6 | P50406 | 1/20 | 0.79 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2215628 | 0.99 | HTR2A (0.81) | HTR2AHTR2CSLC6A4DRD2DRD4 | |
| SCHEMBL12514245 | 0.98 | HTR2A (0.85) | HTR2AHTR2CSLC6A4DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL2213455 | 0.97 | HTR2A (0.85) | HTR2AHTR2CSLC6A4DRD2DRD4 | |
| SCHEMBL12514241 | 0.94 | HTR2A (0.82) | HTR2AHTR2CSLC6A4DRD2DRD4 | |
| SCHEMBL12514906 | 0.94 | HTR2A (0.70) | HTR2AHTR2CSLC6A4DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL2216015 | 0.94 | HTR2A (0.81) | HTR2AHTR2CSLC6A4DRD2DRD4 | |
| SCHEMBL12441249 | 0.92 | HTR2A (0.95) | HTR2AHTR2CSLC6A4DRD2DRD4 | |
| SCHEMBL12441269 | 0.92 | HTR2A (0.86) | HTR2AHTR2CSLC6A4DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL2217646 | 0.91 | HTR2A (0.95) | HTR2AHTR2CSLC6A4DRD2DRD4 | |
| SCHEMBL12441240 | 0.91 | HTR2A (0.95) | HTR2AHTR2CSLC6A4DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895558-B2 | Arylpiperazine-containing pyrrole 3-carboxamide derivatives for treating depressive disorders | GREEN CROSS CORPORATION (KR) | 2014-11-25 | — | — | US | disclosed |