⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15525795 | 0.93 | PNP (0.32) | — | |
| SCHEMBL18558183 | 0.93 | PNP (0.32) | — | |
| SCHEMBL15525797 | 0.93 | PNP (0.32) | — | |
| SCHEMBL16257610 | 0.86 | — | — | |
| SCHEMBL6917371 | 0.81 | MTAP (0.42) | — | |
| SCHEMBL15525761 | 0.79 | — | — | |
| SCHEMBL15525862 | 0.79 | — | — | |
| SCHEMBL15525861 | 0.79 | — | — | |
| SCHEMBL15525347 | 0.79 | PNP (0.35) | — | |
| SCHEMBL15525348 | 0.79 | PNP (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137429-A1 | ANTI-INFLUENZA COMPOSITIONS AND METHODS | BIOCRYST PHARMACEUTICALS, INC. | 2017-05-18 | — | — | US | disclosed |
| US-20170137429-A1 | ANTI-INFLUENZA COMPOSITIONS AND METHODS | BIOCRYST PHARMACEUTICALS, INC. | 2017-05-18 | — | — | US | disclosed |
| US-9499554-B2 | Anti-influenza compositions and methods | BIOCRYST PHARMACEUTICALS, INC. (US) | 2016-11-22 | — | — | US | disclosed |
| US-9499554-B2 | Anti-influenza compositions and methods | BIOCRYST PHARMACEUTICALS, INC. (US) | 2016-11-22 | — | — | US | disclosed |
| US-20160096842-A1 | ANTI-INFLUENZA COMPOSITIONS AND METHODS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2016-04-07 | — | — | US | disclosed |
| US-20160096842-A1 | ANTI-INFLUENZA COMPOSITIONS AND METHODS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2016-04-07 | — | — | US | disclosed |
| WO-2014186465-A1 | ANTI-INFLUENZA COMPOSITIONS AND METHODS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2014-11-20 | — | — | WO | disclosed |