Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 2/20 | 0.39 |
| ▸ | BMP1 | P13497 | 1/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.37 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16257629 | 0.93 | POLB (0.41) | POLBABL1RIN1NT5EBMP1 | |
| SCHEMBL12724973 | 0.91 | POLB (0.44) | POLBABL1RIN1NT5EBMP1 | |
| SCHEMBL13897163 | 0.91 | POLB (0.44) | POLBABL1RIN1NT5EBMP1 | |
| SCHEMBL16257667 | 0.89 | POLB (0.56) | POLBABL1RIN1NT5EP2RY6 | |
| SCHEMBL12724972 | 0.89 | POLB (0.56) | POLBABL1RIN1NT5EP2RY6 | |
| SCHEMBL13213644 | 0.85 | POLB (0.40) | POLBABL1RIN1NT5EBMP1 | |
| SCHEMBL16417877 | 0.83 | ADORA1 (0.42) | — | |
| SCHEMBL12724971 | 0.81 | POLB (0.46) | POLBABL1RIN1NT5EBMP1 | |
| SCHEMBL13897166 | 0.81 | POLB (0.46) | POLBABL1RIN1NT5EBMP1 | |
| SCHEMBL14719079 | 0.81 | POLB (0.60) | POLBABL1RIN1NT5EP2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889843-B2 | Nucleic acid synthesizing dimer amidite and nucleic acid synthesizing method | APTA BIOSCIENCES LTD. (GB) | 2014-11-18 | — | — | US | disclosed |