SCHEMBL16258102

SCHEMBL16258102

CCCCC1CCC(c2cc(F)c(-c3cc(F)c(F)c(F)c3)c(F)c2)CC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.35
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
MAPK1 P28482 4/20 0.33
GAA P10253 3/20 0.33
CYP2C9 P11712 2/20 0.33
MAPT P10636 4/20 0.32
LMNA P02545 2/20 0.32
ALDH1A1 P00352 1/20 0.32
TP53 P04637 4/20 0.32
POLB P06746 1/20 0.32
NPC1 O15118 1/20 0.32
CYP2D6 P10635 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
CYP2C19 P33261 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HTT P42858 1/20 0.31
NAAA Q02083 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16488485 0.96 CYP1A2 (0.33) CYP1A2MEN1KMT2AMAPK1GAA
SCHEMBL8735041 0.96 MEN1 (0.38) CYP1A2MEN1KMT2AMAPK1GAA
SCHEMBL16258101 0.96 MEN1 (0.38) CYP1A2MEN1KMT2AMAPK1GAA
SCHEMBL8735043 0.96 MEN1 (0.38) CYP1A2MEN1KMT2AMAPK1GAA
SCHEMBL8735047 0.96 MEN1 (0.38) CYP1A2MEN1KMT2AMAPK1GAA
SCHEMBL16521131 0.92 MEN1 (0.36) MEN1KMT2AGAACYP2C9MAPT
SCHEMBL15965526 0.92 CYP2C9 (0.40) MEN1KMT2AMAPK1CYP2C9MAPT
SCHEMBL9763896 0.91 CYP1A2 (0.41) CYP1A2MEN1KMT2AMAPK1GAA
SCHEMBL8862221 0.91 CYP1A2 (0.41) CYP1A2MEN1KMT2AMAPK1GAA
SCHEMBL7913637 0.90 CYP1A2 (0.40) CYP1A2MEN1KMT2AMAPK1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed
US-20170355906-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-12-14 US disclosed
US-20170355906-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-12-14 US disclosed
US-9828549-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-11-28 US disclosed
US-9828549-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-11-28 US disclosed
US-9822304-B2 Liquid crystal composition and liquid crystal display element containing the same DIC CORPORATION (JP) 2017-11-21 US disclosed
US-9822304-B2 Liquid crystal composition and liquid crystal display element containing the same DIC CORPORATION (JP) 2017-11-21 US disclosed
US-20170327742-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2017-11-16 US disclosed
US-20170327742-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2017-11-16 US disclosed
EP-3239273-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC Corporation (JP) 2017-11-01 EP disclosed
US-20150159089-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2015-06-11 US disclosed
US-20150159089-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2015-06-11 US disclosed
US-20150108403-A1 Liquid crystal composition and liquid crystal display element DIC CORPORATION (JP) 2015-04-23 US disclosed
US-20150108403-A1 Liquid crystal composition and liquid crystal display element DIC CORPORATION (JP) 2015-04-23 US disclosed
US-20150053891-A1 FLUOROBIPHENYL-CONTAINING COMPOSITION DIC CORPORATION (JP) 2015-02-26 US disclosed
US-20150053891-A1 FLUOROBIPHENYL-CONTAINING COMPOSITION DIC CORPORATION (JP) 2015-02-26 US disclosed
EP-2837670-A1 FLUOROBIPHENYL-CONTAINING COMPOSITION DIC Corporation (JP) 2015-02-18 EP disclosed
US-20150001444-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING SAME DIC CORPORATION (JP) 2015-01-01 US disclosed
US-20150001444-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING SAME DIC CORPORATION (JP) 2015-01-01 US disclosed
EP-2806011-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC Corporation (JP) 2014-11-26 EP disclosed