Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.49 |
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.42 |
| ▸ | DPP4 | P27487 | 4/20 | 0.41 |
| ▸ | CTSS | P25774 | 4/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3139804 | 0.88 | AAK1 (0.43) | CTSKAAK1DPP4CTSSATM | |
| SCHEMBL14550113 | 0.84 | DPP4 (0.47) | CTSKAAK1DPP4CTSSATM | |
| SCHEMBL27800588 | 0.84 | DPP4 (0.47) | CTSKAAK1DPP4CTSSATM | |
| SCHEMBL27800590 | 0.84 | DPP4 (0.47) | CTSKAAK1DPP4CTSSATM | |
| SCHEMBL18133088 | 0.81 | DPP4 (0.43) | CTSKAAK1DPP4CTSSATM | |
| SCHEMBL3138157 | 0.81 | DPP4 (0.43) | CTSKAAK1DPP4CTSSATM | |
| SCHEMBL344600 | 0.81 | DPP4 (0.43) | CTSKAAK1DPP4CTSSATM | |
| SCHEMBL19500634 | 0.81 | DPP4 (0.43) | CTSKAAK1DPP4CTSSATM | |
| SCHEMBL342708 | 0.81 | DPP4 (0.43) | CTSKAAK1DPP4CTSSATM | |
| SCHEMBL29364846 | 0.81 | DPP4 (0.43) | CTSKAAK1DPP4CTSSATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230241-B1 | TETRAHYDRO-IMIDAZO[1,5-A]PYRAZINE DERIVATIVES, PREPARATION METHODS AND MEDICAL USES THEREOF | JIANGSU HENGRUI MEDICINE CO (CN) | 2014-11-26 | — | — | EP | disclosed |