Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.69 |
| ▸ | DPP8 | Q6V1X1 | 13/20 | 0.58 |
| ▸ | DPP7 | Q9UHL4 | 12/20 | 0.57 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10160868 | 0.92 | DPP4 (0.69) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL13175152 | 0.92 | DPP4 (0.69) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL10160870 | 0.92 | DPP4 (0.69) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL10160873 | 0.92 | DPP4 (0.69) | DPP4DPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL2853313 | 0.91 | DPP4 (0.68) | DPP4DPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL2856918 | 0.91 | DPP4 (0.68) | DPP4DPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL27791230 | 0.91 | DPP4 (0.68) | DPP4DPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL2853314 | 0.91 | DPP4 (0.68) | DPP4DPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL2853310 | 0.91 | DPP4 (0.68) | DPP4DPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL2859585 | 0.91 | DPP4 (0.68) | DPP4DPP8DPP7DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230241-B1 | TETRAHYDRO-IMIDAZO[1,5-A]PYRAZINE DERIVATIVES, PREPARATION METHODS AND MEDICAL USES THEREOF | JIANGSU HENGRUI MEDICINE CO (CN) | 2014-11-26 | — | — | EP | disclosed |