Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 14/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16258320 | 1.00 | CETP (0.41) | CETPTP53MAPTACHENAMPT | |
| SCHEMBL663842 | 0.93 | CETP (0.41) | CETPTP53MAPTNAMPT | |
| SCHEMBL663260 | 0.93 | CETP (0.41) | CETPTP53MAPTNAMPT | |
| SCHEMBL663259 | 0.93 | CETP (0.41) | CETPTP53MAPTNAMPT | |
| SCHEMBL663844 | 0.93 | CETP (0.41) | CETPTP53MAPTNAMPT | |
| SCHEMBL663843 | 0.93 | CETP (0.41) | CETPTP53MAPTNAMPT | |
| SCHEMBL663258 | 0.93 | CETP (0.41) | CETPTP53MAPTNAMPT | |
| SCHEMBL663474 | 0.87 | CETP (0.40) | CETP | |
| SCHEMBL663868 | 0.87 | CETP (0.40) | CETP | |
| SCHEMBL663865 | 0.87 | CETP (0.39) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536733-B1 | TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION | BOEHRINGER INGELHEIM INT (DE) | 2014-11-26 | — | — | EP | disclosed |