Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 11/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10196449 | 1.00 | CETP (0.40) | CETPCYP19A1BCHE | |
| SCHEMBL16359992 | 0.92 | CETP (0.34) | CETP | |
| SCHEMBL10196417 | 0.92 | CETP (0.34) | CETP | |
| SCHEMBL663282 | 0.91 | CETP (0.42) | CETP | |
| SCHEMBL16360228 | 0.89 | CETP (0.39) | CETP | |
| SCHEMBL663471 | 0.89 | CETP (0.39) | CETP | |
| SCHEMBL663473 | 0.89 | CETP (0.39) | CETP | |
| SCHEMBL16360319 | 0.89 | CETP (0.39) | CETP | |
| SCHEMBL663865 | 0.89 | CETP (0.39) | CETP | |
| SCHEMBL663867 | 0.89 | CETP (0.39) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536733-B1 | TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION | BOEHRINGER INGELHEIM INT (DE) | 2014-11-26 | — | — | EP | disclosed |
| WO-2011101424-A1 | TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-25 | — | — | WO | disclosed |