SCHEMBL16260441

SCHEMBL16260441

c1ccc(-c2cc(-n3c4ccccc4c4ccc(-n5c6ccccc6c6c5ccc5c7ccccc7n(-c7ccccc7)c56)cc43)nc(-c3ccccc3)n2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.40
MAPK1 P28482 3/20 0.40
TSHR P16473 2/20 0.40
HSD17B10 Q99714 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
HPGD P15428 3/20 0.39
KDM4E B2RXH2 4/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
ATM Q13315 1/20 0.38
LMNA P02545 2/20 0.33
HTT P42858 1/20 0.33
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
ALDH1A1 P00352 2/20 0.31
NTSR1 P30989 1/20 0.31
PIK3CA P42336 2/20 0.30
PIK3CB P42338 1/20 0.30
PIK3CG P48736 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21017465 0.97 MAPT (0.41) MAPTMAPK1TSHRHSD17B10NPSR1
SCHEMBL16260427 0.96 MAPT (0.38) MAPTMAPK1TSHRHSD17B10NPSR1
SCHEMBL25966256 0.96 MAPT (0.39) MAPTMAPK1TSHRHSD17B10NPSR1
SCHEMBL25966280 0.96 MAPT (0.39) MAPTMAPK1TSHRHSD17B10NPSR1
SCHEMBL17248256 0.95 MAPT (0.41) MAPTMAPK1TSHRHSD17B10NPSR1
SCHEMBL25966275 0.93 KDM4E (0.38) MAPTMAPK1TSHRHSD17B10NPSR1
SCHEMBL25966250 0.93 KDM4E (0.38) MAPTMAPK1TSHRHSD17B10NPSR1
SCHEMBL21017475 0.93 MAPT (0.39) MAPTMAPK1TSHRHSD17B10NPSR1
SCHEMBL21365766 0.93 MAPT (0.40) MAPTMAPK1TSHRHSD17B10NPSR1
SCHEMBL21671487 0.93 MAPT (0.40) MAPTMAPK1TSHRHSD17B10NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140346483-A1 COMPOUND FOR AN ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME, AND DISPLAY DEVICE COMPRISING THE ORGANIC LIGHT-EMITTING ELEMENT CHEIL INDUSTRIES, INC. (KR) 2014-11-27 US disclosed
US-20140346483-A1 COMPOUND FOR AN ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME, AND DISPLAY DEVICE COMPRISING THE ORGANIC LIGHT-EMITTING ELEMENT CHEIL INDUSTRIES, INC. (KR) 2014-11-27 US disclosed