Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL162680

O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.[Bi+3]

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

HRH2

The experimentally established mechanism targets of Trifluoromethanesulfonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA7 P43166 1/20 0.44
CA13 Q8N1Q1 1/20 0.44
GPR3 P46089 2/20 0.42
ACHE P22303 2/20 0.33
KCNH2 Q12809 6/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
KMT2A Q03164 1/20 0.31
F2 P00734 1/20 0.30
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL5960768 1.00 CA1 (0.44) CA1CA2CA7CA13GPR3
Trifluoromethanesulfonic Acid SCHEMBL6683175 1.00 CA1 (0.44) CA1CA2CA7CA13GPR3
Trifluoromethanesulfonic Acid SCHEMBL6744412 0.96 CA1 (0.41) CA1CA2CA7CA13GPR3
Trifluoromethanesulfonic Acid SCHEMBL18835233 0.96 CA1 (0.41) CA1CA2CA7CA13GPR3
Trifluoromethanesulfonic Acid SCHEMBL5960808 0.96 CA1 (0.41) CA1CA2CA7CA13GPR3
Trifluoromethanesulfonic Acid SCHEMBL5795370 0.96 CA1 (0.41) CA1CA2CA7CA13GPR3
Trifluoromethanesulfonic Acid SCHEMBL25285896 0.92 CA1 (0.44) CA1CA2CA7CA13GPR3
Trifluoromethanesulfonic Acid SCHEMBL25287606 0.92 CA1 (0.44) CA1CA2CA7CA13GPR3
Trifluoromethanesulfonic Acid SCHEMBL25301943 0.92 CA1 (0.44) CA1CA2CA7CA13GPR3
Trifluoromethanesulfonic Acid SCHEMBL23430060 0.92 CA1 (0.44) CA1CA2CA7CA13GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2464 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079748-A Guaazulene triarylmethane, synthesis method and application thereof in preparation of antibacterial products 2026-05-26 CN claimed
CN-117440957-B Process for the production of biotin intermediates DSM IP ASSETS B.V. (NL) 2026-05-26 CN claimed
CN-122059808-A Method for selectively synthesizing isopentenyl phenol compounds 兰州石化职业技术大学 2026-05-19 CN claimed
CN-122010956-A Chiral 1, 4-diazabicyclo [3.1.1] heptane derivatives, synthesis and application thereof 浙江师范大学 2026-05-12 CN claimed
CN-122010969-A Aminated 20 (S) -10, 11-difluoro methylenedioxy camptothecin derivative, and preparation method and application thereof 浙江工业大学 2026-05-12 CN claimed
EP-4724512-A1 METHOD FOR SYNTHESISING A GLYCEROL POLYESTER AND GLYCEROL POLYESTER OBTAINED THEREBY COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2026-04-15 EP claimed
EP-4015592-B1 CURABLE CONDENSATION COMPOUNDS ON THE BASIS OF ALKOXY-FUNCTIONAL POLYSILOXANES EVONIK OPERATIONS GMBH (DE) 2026-03-18 EP claimed
EP-4685150-A1 METHOD FOR PRODUCING AMIDE GROUP-CONTAINING COMPOUND USING N-CARBOXYAMINO ACID ANHYDRIDE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2026-01-28 EP claimed
US-20250368599-A1 PROCESS FOR THE PREPARATION OF CYCLOHOMOGERANATES BASF SE (DE) 2025-12-04 US claimed
US-12460081-B2 Curable condensation compounds based on alkoxy-functional polysiloxanes EVONIK OPERATIONS GMBH (DE) 2025-11-04 US claimed
WO-2003085071-A1 PREPARATION OF LEVULINIC ACID ESTERS AND FORMIC ACID ESTERS FROM BIOMASS AND OLEFINS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-10-16 WO claimed
US-6608232-B1 Acylating an aromatic compound in presence of zeolite or friedel crafts catalyst, reduction to a carbinol and cata-lytic etherification Chimie, Rhodia (FR) 2003-08-19 US claimed
US-20030109724-A1 Manufacture of 3-methyl-tetrahydrofuran from alpha-methylene-gamma-butyrolactone in a two step process INVISTA NORTH AMERICA S.A.R.L. 2003-06-12 US claimed
US-20030065198-A1 By hydrogenation INVISTA NORTH AMERICA S.A.R.L. 2003-04-03 US claimed
US-6348631-B1 REACTING AROMATIC COMPOUND WITH ACYLATING OR SULFONYLATING AGENT IN PRESENCE OF FRIEDEL-CRAFTS CATALYST, WHEREIN ACYLATION OR SULFONYLATION REACTION IS CARRIED OUT IN LIQUID PHASE UNDER MICROWAVE IRRADIATION RHODIA CHIMIE (FR) 2002-02-19 US claimed
US-20020010374-A1 Continuous process for the preparation of polytrimethylene ether glycol DUPONT INDUSTRIAL BIOSCIENCES USA, LLC 2002-01-24 US claimed
EP-0877726-B1 AROMATIC COMPOUND ACYLATION METHOD RHODIA CHIMIE SA (FR) 2001-12-12 EP claimed
WO-2001000552-A9 SELECTIVE ALKANOL ALKOXYLATIONS PROCESS UNION CARBIDE CHEM PLASTIC (US) 2001-06-21 WO claimed
WO-2001000552-A1 SELECTIVE ALKANOL ALKOXYLATIONS PROCESS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2001-01-04 WO claimed
CN-1249737-A Method for acylation or sulphonation of aromatic compound RHODIA CHIMIE SA (FR) 2000-04-05 CN claimed