Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16273658 | 0.91 | HSP90AA1 (0.38) | MRGPRX4HSP90AA1TP53HTTKDM4E | |
| SCHEMBL16273648 | 0.91 | HSP90AA1 (0.37) | MRGPRX4HSP90AA1HDAC8KDM4EPTGER1 | |
| SCHEMBL16273647 | 0.88 | MRGPRX4 (0.40) | MRGPRX4HSP90AA1TP53HTTKDM4E | |
| SCHEMBL17616610 | 0.87 | MEN1 (0.35) | MRGPRX4HSP90AA1TP53HTTHDAC8 | |
| SCHEMBL17616573 | 0.86 | FFAR1 (0.34) | MRGPRX4HSP90AA1TP53HDAC8KDM4E | |
| SCHEMBL17616596 | 0.83 | FFAR1 (0.36) | MRGPRX4HSP90AA1TP53HTTKDM4E | |
| SCHEMBL17616571 | 0.83 | MRGPRX4 (0.40) | MRGPRX4TP53HTTKDM4EPTGER1 | |
| SCHEMBL16273759 | 0.80 | MRGPRX4 (0.42) | MRGPRX4TP53HTTHDAC8KDM4E | |
| SCHEMBL16273645 | 0.80 | HSP90AA1 (0.39) | HSP90AA1COMT | |
| SCHEMBL16273754 | 0.79 | HSP90AA1 (0.44) | HSP90AA1PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9675072-B2 | Tetrazolinone compound and application of same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-06-13 | — | — | US | disclosed |
| WO-2015016373-A1 | TETRAZOLINONE COMPOUND, AND USE THEREFOR | 住友化学株式会社 (JP) | 2015-02-05 | — | — | WO | disclosed |
| WO-2014192953-A1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | 住友化学株式会社 (JP) | 2014-12-04 | — | — | WO | disclosed |