SCHEMBL16275486

SCHEMBL16275486

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-n4c5ccccc5c5c6oc7ccccc7c6c6c(c7ccccc7n6-c6ccccc6)c54)cc3)n2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.38
TSHR P16473 3/20 0.38
ALDH1A1 P00352 6/20 0.38
PPARG P37231 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
NR2E3 Q9Y5X4 1/20 0.38
NCOR2 Q9Y618 1/20 0.38
KDM4E B2RXH2 5/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
LMNA P02545 6/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
POLB P06746 3/20 0.36
HPGD P15428 1/20 0.36
HSD17B10 Q99714 2/20 0.36
MAPK1 P28482 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16275731 1.00 MAPT (0.38) MAPTTSHRALDH1A1PPARGRXFP1
SCHEMBL16275357 0.96 MAPT (0.39) MAPTTSHRALDH1A1PPARGRXFP1
SCHEMBL17405368 0.95 MAPT (0.38) MAPTTSHRALDH1A1PPARGRXFP1
SCHEMBL17405776 0.95 MAPT (0.38) MAPTTSHRALDH1A1PPARGRXFP1
SCHEMBL17405911 0.94 MAPT (0.38) MAPTTSHRALDH1A1PPARGRXFP1
SCHEMBL17406161 0.94 MAPT (0.38) MAPTTSHRALDH1A1PPARGRXFP1
SCHEMBL17406078 0.94 MAPT (0.38) MAPTTSHRALDH1A1PPARGRXFP1
SCHEMBL17405302 0.94 MAPT (0.38) MAPTTSHRALDH1A1PPARGRXFP1
SCHEMBL16275297 0.94 MAPT (0.38) MAPTTSHRALDH1A1PPARGRXFP1
SCHEMBL16275280 0.94 MAPT (0.38) MAPTTSHRALDH1A1PPARGRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9991445-B2 Heterocyclic compound, material for organic electroluminescence device including the same, and organic electroluminescence device and electronic equipment employing the same IDEMITSU KOSAN CO., LTD. (JP) 2018-06-05 US disclosed
US-9991445-B2 Heterocyclic compound, material for organic electroluminescence device including the same, and organic electroluminescence device and electronic equipment employing the same IDEMITSU KOSAN CO., LTD. (JP) 2018-06-05 US disclosed
US-20140353640-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-12-04 US disclosed
US-20140353640-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-12-04 US disclosed