Cyclooctene

Cyclooctene

SCHEMBL1627600

C1=C\CCCCCC/1.C=C(C)C(=O)O

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL10397426 1.00 TDP1 (0.33) TDP1
Cyclooctene SCHEMBL1627602 1.00 TDP1 (0.33) TDP1
Cyclohexene SCHEMBL2937014 0.97 TDP1 (0.35) TDP1
Cyclohexene SCHEMBL8664894 0.97 TDP1 (0.35) TDP1
Methacrylic Acid SCHEMBL3674253 0.92 TDP1 (0.35) TDP1
Methacrylic Acid SCHEMBL27648805 0.92 TDP1 (0.35) TDP1
Methacrylic Acid SCHEMBL28392098 0.91 TDP1 (0.31) TDP1
Methacrylic Acid SCHEMBL27889970 0.90 TDP1 (0.33) TDP1
Methacrylic Acid SCHEMBL1614485 0.86 TDP1 (0.31) TDP1
Methacrylic Acid SCHEMBL10896194 0.85 TDP1 (0.33) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7989544-B2 Amphiphilic polymer capsules and related methods of interfacial assembly UNIVERSITY OF MASSACHUSETTS (US) 2011-08-02 US disclosed
US-20110091533-A1 Amphiphilic polymer capsules and related methods of interfacial assembly NATIONAL SCIENCE FOUNDATION 2011-04-21 US disclosed
US-7851543-B2 Amphiphilic polymer capsules and related methods of interfacial assembly UNIVERSITY OF MASSACHUSETTS (US) 2010-12-14 US disclosed
US-20100036061-A1 Amphiphilic Polymer Capsules and Related Methods of Interfacial Assembly NATIONAL SCIENCE FOUNDATION 2010-02-11 US disclosed
US-7598313-B2 Amphiphilic polymer capsules and related methods of interfacial assembly UNIVERSITY OF MASSACHUSETTS (US) 2009-10-06 US disclosed
EP-1663469-A1 AMPHIPHILIC POLYMER CAPSULES AND RELATED METHODS OF INTERFACIAL ASSEMBLY The University of Massachusetts (US) 2006-06-07 EP disclosed
US-20050096454-A1 Amphiphilic polymer capsules and related methods of interfacial assembly UNIVERSITY OF MASSACHUSETTS 2005-05-05 US disclosed
WO-2005025736-A1 AMPHIPHILIC POLYMER CAPSULES AND RELATED METHODS OF INTERFACIAL ASSEMBLY UNIVERSITY OF MASSACHUSETTS (US) 2005-03-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110091533-A1 Amphiphilic polymer capsules and related methods of interfacial assembly SQLE, COASY, PHOSPHO1 TDP1 4816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.