Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15412490 | 0.79 | POLB (0.41) | POLBKDM4EALDH1A1PTGS1PTGS2 | |
| SCHEMBL15412563 | 0.79 | POLB (0.39) | POLBKDM4EALDH1A1MET | |
| SCHEMBL15412815 | 0.78 | POLB (0.40) | POLBKDM4EALDH1A1PTGS1PTGS2 | |
| SCHEMBL15412578 | 0.77 | POLB (0.39) | POLBKDM4EALDH1A1PTGS2MET | |
| SCHEMBL15412786 | 0.77 | POLB (0.43) | POLBKDM4EALDH1A1MET | |
| SCHEMBL10281053 | 0.76 | POLB (0.40) | POLBKDM4EALDH1A1MET | |
| SCHEMBL16280596 | 0.76 | POLB (0.39) | POLBKDM4EALDH1A1RORCAGPAT2 | |
| SCHEMBL16280594 | 0.76 | POLB (0.39) | POLBKDM4EALDH1A1RORCAGPAT2 | |
| SCHEMBL15412326 | 0.75 | POLB (0.42) | POLBKDM4EALDH1A1MET | |
| SCHEMBL20708497 | 0.72 | POLB (0.45) | POLBGPBAR1KDM4EALDH1A1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140364444-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140364444-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL | NR4A1, NR2C2, NR0B1 | POLB 4737/4885CYP2C9 661/4885GPBAR1 2547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.