Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.92 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL32660710 | 1.00 | TP53 (0.92) | TP53TSHRSLC7A5ALDH1A1LMNA | |
| Lactic Acid SCHEMBL671983 | 1.00 | — | — | |
| Lactic Acid SCHEMBL5364277 | 1.00 | TP53 (0.92) | TP53TSHRSLC7A5ALDH1A1LMNA | |
| Lactic Acid SCHEMBL19463679 | 0.96 | — | — | |
| Lactic Acid SCHEMBL31230586 | 0.96 | TP53 (0.85) | TP53TSHRSLC7A5ALDH1A1LMNA | |
| Lactic Acid SCHEMBL29361800 | 0.96 | — | — | |
| Lactic Acid SCHEMBL11646989 | 0.96 | — | — | |
| Lactic Acid SCHEMBL5189465 | 0.96 | TP53 (1.00) | TP53TSHRSLC7A5ALDH1A1LMNA | |
| Lactic Acid SCHEMBL9066423 | 0.96 | TP53 (1.00) | TP53TSHRSLC7A5ALDH1A1LMNA | |
| L-Lactic Acid SCHEMBL13165963 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7927645-B2 | Enhancing clarity and/or stability properties of protein-containing liquids and gels | NEW ZEALAND DAIRY BOARD (NZ) | 2011-04-19 | — | — | US | disclosed |
| US-20070082118-A1 | Enhancing clarity and/or stability properties of protein-containing liquids and gels | NEW ZEALAND DAIRY BOARD (NZ) | 2007-04-12 | — | — | US | disclosed |
| EP-1631157-A4 | ENHANCING CLARITY AND/OR STABILITY PROPERTIES OF PROTEIN-CONTAINING LIQUIDS AND GELS | NEW ZEALAND DAIRY BOARD (NZ) | 2006-12-27 | — | — | EP | disclosed |
| EP-1631157-A2 | ENHANCING CLARITY AND/OR STABILITY PROPERTIES OF PROTEIN-CONTAINING LIQUIDS AND GELS | NEW ZEALAND DAIRY BOARD (NZ) | 2006-03-08 | — | — | EP | disclosed |
| WO-2004091309-A2 | ENHANCING CLARITY AND/OR STABILITY PROPERTIES OF PROTEIN-CONTAINING LIQUIDS AND GELS | NEW ZEALAND DAIRY BOARD (NZ) | 2004-10-28 | — | — | WO | disclosed |