Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.49 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.44 |
| ▸ | RRM1 | P23921 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 4/20 | 0.40 |
| ▸ | NOS1 | P29475 | 3/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19704052 | 0.86 | KDM4E (0.58) | KDM4EMAPK1HIF1APAOXDPP7 | |
| SCHEMBL26646766 | 0.86 | KDM4E (0.58) | KDM4EMAPK1HIF1APAOXDPP7 | |
| SCHEMBL6060265 | 0.85 | DPP7 (0.46) | KDM4EMAPK1HIF1APAOXDPP7 | |
| SCHEMBL919222 | 0.85 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXDPP7 | |
| SCHEMBL236178 | 0.85 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXDPP7 | |
| SCHEMBL180969 | 0.85 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXDPP7 | |
| Hydrochloric Acid SCHEMBL15669798 | 0.83 | KDM4E (0.54) | KDM4EMAPK1HIF1APAOXDPP7 | |
| SCHEMBL30125060 | 0.83 | KDM4E (0.59) | KDM4EMAPK1HIF1APAOXDPP7 | |
| Hydrochloric Acid SCHEMBL28854969 | 0.83 | KDM4E (0.54) | KDM4EMAPK1HIF1APAOXDPP7 | |
| SCHEMBL20168409 | 0.82 | DPP7 (0.46) | DPP7GNAI3GNAO1GNAI1RRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4392440-A2 | COMBINATION OF RELAXIN AND VASOPRESSIN ANALOGUES FOR TREATMENT OF RENAL DISORDERS OR CONDITIONS | River 2 Renal Corp. (US) | 2024-07-03 | — | — | EP | disclosed |
| WO-2023028008-A2 | COMBINATION OF RELAXIN AND VASOPRESSIN ANALOGUES FOR TREATMENT OF RENAL DISORDERS OR CONDITIONS | RIVER 2 RENAL CORP. (US) | 2023-03-02 | — | — | WO | disclosed |
| US-9376461-B2 | Non-enzymatic synthesis of O-acetyl-ADP-ribose and analogues thereof | GLAXOSMITHKLINE LLC (US) | 2016-06-28 | — | — | US | disclosed |
| US-9193736-B2 | PDE 10a inhibitors for the treatment of type II diabetes | JANSSEN PHARMACEUTICA, NV (BE) | 2015-11-24 | — | — | US | disclosed |
| US-20150218202-A1 | NON-ENZYMATIC SYNTHESIS OF O-ACETYL-ADP-RIBOSE AND ANALOGUES THEREOF | GLAXOSMITHKLINE LLC | 2015-08-06 | — | — | US | disclosed |
| US-20140364413-A1 | PDE 10a Inhibitors for the Treatment of Type II Diabetes | JANSSEN PHARMACEUTICA, NV (BE) | 2014-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140364413-A1 | PDE 10a Inhibitors for the Treatment of Type II Diabetes | PDE2A, PDE3B, PDE3A | KDM4E 1186/4885MAPK1 1519/4885HIF1A 1818/4885 |
| US-20150218202-A1 | NON-ENZYMATIC SYNTHESIS OF O-ACETYL-ADP-RIBOSE AND ANALOGUES THEREOF | SARM1, NADK, CD38 | KDM4E 2119/4885MAPK1 3007/4885HIF1A 3382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.