Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | BPTF | Q12830 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16285527 | 0.98 | TDP1 (0.51) | TDP1MEN1KMT2ARAB9APLK1 | |
| SCHEMBL16285515 | 0.97 | TDP1 (0.53) | TDP1MEN1KMT2ARAB9APLK1 | |
| SCHEMBL16285526 | 0.95 | TDP1 (0.47) | TDP1MEN1KMT2ARAB9APLK1 | |
| SCHEMBL16285503 | 0.95 | TDP1 (0.47) | TDP1MEN1KMT2ARAB9APLK1 | |
| SCHEMBL16285543 | 0.95 | TDP1 (0.47) | TDP1MEN1KMT2ARAB9APLK1 | |
| SCHEMBL16285552 | 0.95 | TDP1 (0.50) | TDP1MEN1KMT2ARAB9APLK1 | |
| SCHEMBL16285493 | 0.95 | PLK1 (0.48) | TDP1MEN1KMT2ARAB9APLK1 | |
| SCHEMBL16285568 | 0.93 | TDP1 (0.46) | TDP1MEN1KMT2APLK1XDH | |
| SCHEMBL16285541 | 0.93 | TDP1 (0.46) | TDP1MEN1KMT2APLK1XDH | |
| SCHEMBL16285533 | 0.93 | TDP1 (0.46) | TDP1MEN1KMT2APLK1XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140361285-A1 | MONOAMINE COMPOUND, CHARGE-TRANSPORTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT DEVICE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2014-12-11 | — | — | US | disclosed |