SCHEMBL16286148

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16286147	0.90	BTK (0.50)	PTK2C5AR1LYNSRCBTK
	SCHEMBL16285686	0.87	LYN (0.46)	LYNSRCBTKCDK4CCND1
	SCHEMBL16286112	0.86	PTK2 (0.45)	PTK2C5AR1EGFRCDK4CCND1
	SCHEMBL10192792	0.83	CDK4 (0.51)	PTK2EGFRCDK4CCND1CCND2
	SCHEMBL16286149	0.82	IDH2 (0.38)	PTK2KIF11
	SCHEMBL16285680	0.78	BTK (0.55)	LYNSRCEGFRBTKCDK4
	SCHEMBL16286126	0.76	CDK4 (0.44)	PTK2C5AR1SRCEGFRBTK
	SCHEMBL16286129	0.75	TDP1 (0.40)	PTK2C5AR1CDK4CCND1GAA
	SCHEMBL10192791	0.74	WEE1 (0.58)	PTK2SRCBTKCDK4CCND1
	SCHEMBL16285663	0.72	CDK4 (0.42)	CDK4CCND1CCND2CCND3KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.