⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20724812 | 0.97 | FFAR1 (0.31) | — | |
| SCHEMBL13082770 | 0.92 | — | — | |
| SCHEMBL13270633 | 0.79 | — | — | |
| SCHEMBL12922724 | 0.77 | — | — | |
| SCHEMBL12214043 | 0.77 | FFAR1 (0.33) | — | |
| SCHEMBL526021 | 0.77 | FFAR1 (0.33) | — | |
| SCHEMBL8057290 | 0.77 | — | — | |
| SCHEMBL14473252 | 0.75 | — | — | |
| SCHEMBL463669 | 0.74 | — | — | |
| SCHEMBL4580892 | 0.74 | TDP1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11701379-B2 | In vitro and in vivo intracellular delivery of siRNA via self-assembled nanopieces | RHODE ISLAND HOSPITAL (US) | 2023-07-18 | — | — | US | disclosed |
| US-20210023117-A1 | IN VITRO AND IN VIVO INTRACELLULAR DELIVERY OF SIRNA VIA SELF-ASSEMBLED NANOPIECES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-01-28 | — | — | US | disclosed |
| US-10555948-B2 | Nanocarriers and their processing for diagnostics and therapeutics | RHODE ISLAND HOSPITAL (US) | 2020-02-11 | — | — | US | disclosed |
| US-10201634-B2 | Nanotubes and compositions thereof | BROWN UNIVERSITY (US) | 2019-02-12 | — | — | US | disclosed |
| US-20180193344-A1 | Nanocarriers And Their Processing For Diagnostics And Therapeutics | RHODE ISLAND HOSPITAL | 2018-07-12 | — | — | US | disclosed |
| US-20110091353-A1 | Methods for Sterilizing Tissue | BURGESS WILSON | 2011-04-21 | — | — | US | disclosed |
| US-7848487-B2 | Methods for sterilizing biological materials containing non-aqueous solvents | CLEARANT, INC. (US) | 2010-12-07 | — | — | US | disclosed |
| US-20090214382-A1 | Methods of sterilizing biological mixtures using alpha-keto acids | CLEARANT, INC. | 2009-08-27 | — | — | US | disclosed |
| US-20090202039-A1 | Methods for Sterilizing Biological Materials Containing Non-Aqueous Solvents | MIEKKA SHIRLEY | 2009-08-13 | — | — | US | disclosed |
| US-20080080998-A1 | Propylene glycol, dimethyl sulfoxide, trehalose and mannitol and gamma radiation; reduce active biological contaminants or pathogens in bone; reduce post-implantation complications, inflammation, immune rejection reactions, calcification | CLEARANT, INC. | 2008-04-03 | — | — | US | disclosed |
| US-20030095890-A1 | Methods for sterilizing biological materials containing non-aqueous solvents | CLEARANT, INC. | 2003-05-22 | — | — | US | disclosed |
| WO-2003035238-A2 | METHODS FOR COMBATING BIO-TERRORISM | CLEARANT, INC. (US) | 2003-05-01 | — | — | WO | disclosed |
| WO-2003030949-A1 | METHODS OF STERILIZING BIOLOGICAL MATERIALS | CLEARANT INC. (US) | 2003-04-17 | — | — | WO | disclosed |
| WO-2003026705-A1 | METHODS FOR STERILIZING BIOLOGICAL MATERIALS USING FLAVONOID/FLAVONOL STABILIZERS | CLEARANT, INC. (US) | 2003-04-03 | — | — | WO | disclosed |
| US-20030064000-A1 | Methods of sterilizing biological mixtures using stabilizer mixtures | CLEARANT, INC. | 2003-04-03 | — | — | US | disclosed |
| WO-2003026704-A1 | METHODS OF STERILIZING BIOLOGICAL MIXTURES USING STABILIZER MIXTURES | CLEARANT, INC. (US) | 2003-04-03 | — | — | WO | disclosed |
| WO-2003026769-A2 | METHODS FOR STERILIZING PREPARATIONS OF GLYCOSIDASES | CLEARANT, INC. (US) | 2003-04-03 | — | — | WO | disclosed |
| US-20030059338-A1 | Methods for sterilizing biological materials using flavonoid/flavonol stabilizers | CLEARANT, INC. | 2003-03-27 | — | — | US | disclosed |
| US-20030059920-A1 | Methods for sterilizing preparations of glycosidases | CLEARANT, INC. | 2003-03-27 | — | — | US | disclosed |
| US-20030012687-A1 | Methods of sterilizing biological materials | CLEARANT, INC. | 2003-01-16 | — | — | US | disclosed |