Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 15/20 | 0.49 |
| ▸ | PTGIS | Q16647 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PDE9A | O76083 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16290098 | 1.00 | TBXA2R (0.56) | TBXA2RCYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL12330065 | 1.00 | TBXA2R (0.56) | TBXA2RCYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL12329694 | 0.88 | TBXA2R (0.54) | TBXA2RCYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL16290182 | 0.88 | TBXA2R (0.65) | TBXA2RCYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL12330325 | 0.88 | TBXA2R (0.65) | TBXA2RCYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL16290072 | 0.88 | TBXA2R (0.65) | TBXA2RCYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL12444481 | 0.88 | TBXA2R (0.59) | TBXA2RCYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL12330025 | 0.87 | TBXA2R (0.74) | TBXA2RCYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL2934089 | 0.86 | TBXA2R (0.76) | TBXA2RCYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL2941082 | 0.86 | TBXA2R (0.76) | TBXA2RCYP1A2CYP3A4MEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976509-B1 | PPAR MODULATORS | EVOLVA SA (CH) | 2014-12-17 | — | — | EP | claimed |