Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.73 |
| ▸ | S1PR3 | Q99500 | 13/20 | 0.73 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.59 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL947401 | 0.99 | S1PR1 (0.73) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL947989 | 0.92 | S1PR1 (0.80) | S1PR1S1PR3 | |
| SCHEMBL16290118 | 0.91 | S1PR1 (0.84) | S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL949682 | 0.91 | S1PR1 (0.77) | S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL950427 | 0.90 | S1PR1 (0.84) | S1PR1S1PR3 | |
| SCHEMBL949690 | 0.89 | S1PR1 (0.70) | S1PR1S1PR3 | |
| SCHEMBL676646 | 0.89 | S1PR1 (0.84) | S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL951171 | 0.88 | S1PR1 (0.85) | S1PR1S1PR3 | |
| SCHEMBL16290125 | 0.88 | S1PR1 (0.80) | S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL951169 | 0.87 | S1PR1 (0.80) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1661881-B1 | COMPOUND CAPABLE OF BINDING S1P RECEPTOR AND PHARMACEUTICAL USE THEREOF | ONO PHARMACEUTICAL CO (JP) | 2014-12-17 | — | — | EP | claimed |
| EP-1661881-B1 | COMPOUND CAPABLE OF BINDING S1P RECEPTOR AND PHARMACEUTICAL USE THEREOF | ONO PHARMACEUTICAL CO (JP) | 2014-12-17 | — | — | EP | disclosed |