Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 6/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.52 |
| ▸ | PDE4A | P27815 | 3/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15809933 | 1.00 | PDE4D (0.52) | PDE4DPDE4BPDE4APDE4CKMT2A | |
| SCHEMBL15809932 | 0.97 | PDE4D (0.50) | PDE4DPDE4BPDE4APDE4CKMT2A | |
| SCHEMBL16290196 | 0.97 | PDE4D (0.50) | PDE4DPDE4BPDE4APDE4CKMT2A | |
| SCHEMBL2046669 | 0.89 | PDE4D (0.57) | PDE4DPDE4BPDE4APDE4CKMT2A | |
| SCHEMBL13721383 | 0.89 | PDE4D (0.57) | PDE4DPDE4BPDE4APDE4CKMT2A | |
| SCHEMBL2043102 | 0.89 | PDE4D (0.57) | PDE4DPDE4BPDE4APDE4CKMT2A | |
| SCHEMBL13721007 | 0.86 | PDE4D (0.55) | PDE4DPDE4BPDE4APDE4CKMT2A | |
| SCHEMBL13721005 | 0.86 | PDE4D (0.55) | PDE4DPDE4BPDE4APDE4CKMT2A | |
| SCHEMBL2043775 | 0.86 | PDE4D (0.55) | PDE4DPDE4BPDE4APDE4CKMT2A | |
| SCHEMBL15810008 | 0.85 | PDE4D (0.53) | PDE4DPDE4BPDE4APDE4CKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2813509-A1 | 3,4,4a,10b-tetrahydro-1h-thiopyrano-[4,3-c]isoquinoline derivatives | Takeda GmbH (DE) | 2014-12-17 | — | — | EP | disclosed |