Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.44 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butadiene SCHEMBL16290288 | 1.00 | TSHR (0.44) | TSHRGABRR1GABRR2BLMLMNA | |
| SCHEMBL193238 | 0.89 | — | — | |
| SCHEMBL5077461 | 0.89 | — | — | |
| SCHEMBL31609 | 0.89 | — | — | |
| Charcoal, Activated SCHEMBL31265614 | 0.87 | — | — | |
| SCHEMBL31339493 | 0.87 | — | — | |
| Charcoal, Activated SCHEMBL31347514 | 0.87 | TSHR (0.50) | TSHRGABRR1GABRR2BLMLMNA | |
| Hydrochloric Acid SCHEMBL10892534 | 0.87 | — | — | |
| Methane SCHEMBL28824174 | 0.87 | — | — | |
| SCHEMBL30027441 | 0.87 | TSHR (0.50) | TSHRGABRR1GABRR2BLMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791342-B1 | MODIFIED MICROORGANISMS AND METHODS OF MAKING BUTADIENE USING SAME | BRASKEM SA (BR) | 2020-04-29 | — | — | EP | disclosed |
| US-10273505-B2 | Modified microorganisms and methods of making butadiene using same | BRASKEM S.A. (BR) | 2019-04-30 | — | — | US | disclosed |
| US-20180346936-A1 | MODIFIED MICROORGANISMS AND METHODS OF MAKING BUTADIENE USING SAME | BRASKEM S.A. (BR) | 2018-12-06 | — | — | US | disclosed |
| US-10059963-B2 | Modified microorganisms and methods of making butadiene using same | BRASKEM S.A. (BR) | 2018-08-28 | — | — | US | disclosed |
| US-9518273-B2 | Modified microorganisms and methods of making butadiene using same | BRASKEM S.A. (BR) | 2016-12-13 | — | — | US | disclosed |
| US-20160032325-A1 | MODIFIED MICROORGANISMS AND METHODS OF MAKING BUTADIENE USING SAME | BRASKEM S.A. (BR) | 2016-02-04 | — | — | US | disclosed |
| US-20150152439-A2 | MODIFIED MICROORGANISMS AND METHODS OF MAKING BUTADIENE USING SAME | BRASKEM S.A. (BR) | 2015-06-04 | — | — | US | disclosed |
| US-20140370564-A1 | MODIFIED MICROORGANISMS AND METHODS OF MAKING BUTADIENE USING SAME | BRASKEM SA (BR) | 2014-12-18 | — | — | US | disclosed |