SCHEMBL162925

SCHEMBL162925

O=c1[nH]cnc2ccc3cc4ccccc4cc3c12

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 10/20 0.49
PDPK1 O15530 1/20 0.49
CA12 O43570 1/20 0.49
ALOX15 P16050 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
CA9 Q16790 1/20 0.49
TNKS2 Q9H2K2 1/20 0.49
ACVR1 Q04771 3/20 0.45
IP6K1 Q92551 4/20 0.45
IP6K3 Q96PC2 3/20 0.44
IP6K2 Q9UHH9 3/20 0.44
CHEK1 O14757 1/20 0.44
PIM1 P11309 1/20 0.44
AKT1 P31749 1/20 0.44
FLT3 P36888 1/20 0.44
PIM3 Q86V86 1/20 0.44
TYMS P04818 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6674377 0.85 PARP1 (0.58) PARP1PDPK1CA12ALOX15SMN1; SMN2
SCHEMBL8131559 0.83 PARP1 (0.51) PARP1PDPK1CA12ALOX15SMN1; SMN2
SCHEMBL2921734 0.78 PARP1 (0.61) PARP1PDPK1CA12ALOX15SMN1; SMN2
SCHEMBL4138780 0.78 PDPK1 (0.39) PARP1PDPK1CA12ALOX15SMN1; SMN2
SCHEMBL29744436 0.78 PARP1 (0.61) PARP1PDPK1CA12ALOX15SMN1; SMN2
SCHEMBL3731351 0.74 ACVR1 (0.60) PARP1PDPK1CA12ALOX15SMN1; SMN2
SCHEMBL11609746 0.74 TYMS (0.75) TYMS
SCHEMBL4949060 0.72 KDM4A (0.57) PARP1PDPK1CA12ALOX15SMN1; SMN2
SCHEMBL11150595 0.68 CYP3A4 (0.41) SMN1; SMN2TYMS
SCHEMBL1325756 0.68 PI4KA (0.45) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1031 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3935111-B1 CURABLE INK COMPOSITIONS DOMINO PRINTING SCIENCES PLC (GB) 2025-07-23 EP claimed
US-12071556-B2 Curable ink composition DOMINO PRINTING SCIENCES PLC (GB) 2024-08-27 US claimed
EP-3563185-B1 POLARIZING ARTICLE AND METHOD OF FORMING A POLARIZING ARTICLE TRANSITIONS OPTICAL LTD (IE) 2024-01-31 EP claimed
US-20220145109-A1 Curable Ink Composition DOMINO PRINTING SCIENCES PLC (GB) 2022-05-12 US claimed
EP-3935111-A1 CURABLE INK COMPOSITIONS Domino Printing Sciences PLC (GB) 2022-01-12 EP claimed
CN-110114703-B Polarized article and method of forming a polarized article 光学转变有限公司 2022-01-11 CN claimed
EP-2969499-B1 METHOD OF PREPARING PHOTOCHROMIC-DICHROIC FILMS HAVING REDUCED OPTICAL DISTORTION TRANSITIONS OPTICAL INC (US) 2021-12-08 EP claimed
US-10884288-B2 Polarizing article and method of forming a polarizing article TRANSITIONS OPTICAL, LTD. (IE) 2021-01-05 US claimed
EP-2969468-B1 METHOD OF PREPARING PHOTOCHROMIC-DICHROIC FILMS HAVING REDUCED OPTICAL DISTORTION TRANSITIONS OPTICAL INC (US) 2020-12-23 EP claimed
WO-2020182640-A1 CURABLE INK COMPOSITIONS DOMINO PRINTING SCIENCES PLC (GB) 2020-09-17 WO claimed
EP-1147147-A1 A COLORANT COMPOSITION, A POLYMER NANOCOMPOSITE COMPRISING THE COLORANT COMPOSITION AND ARTICLES PRODUCED THEREFROM EASTMAN CHEMICAL COMPANY (US) 2001-10-24 EP claimed
WO-2000034379-A1 A COLORANT COMPOSITION, A POLYMER NANOCOMPOSITE COMPRISING THE COLORANT COMPOSITION AND ARTICLES PRODUCED THEREFROM EASTMAN CHEMICAL COMPANY (US) 2000-06-15 WO claimed
US-5925336-A Aqueous nail coating composition containing copolymerized colorants EASTMAN CHEMICAL COMPANY (US) 1999-07-20 US claimed
EP-0869765-A1 AQUEOUS NAIL COATING COMPOSITION CONTAINING COPOLYMERIZED COLORANTS EASTMAN CHEMICAL COMPANY (US) 1998-10-14 EP claimed
US-5744129-A Aqueous lip gloss and cosmetic compositions containing colored sulfopolyesters EASTMAN CHEMICAL COMPANY 1998-04-28 US claimed
US-5735907-A COLORANT REACTED INTO OR ONTO POLYMER BACKBONE CLAIROL, INC. (US) 1998-04-07 US claimed
WO-1997024102-A1 AQUEOUS NAIL COATING COMPOSITION CONTAINING COPOLYMERIZED COLORANTS EASTMAN CHEMICAL COMPANY (US) 1997-07-10 WO claimed
EP-0747036-A2 A method of coloring hair with, and hair coloring compositions comprising, sulfo-containing water dispersible colored polymers Bristol-Myers Squibb Company (US) 1996-12-11 EP claimed
US-4845220-A Vattable 2-aryl-4,6-diaminopyrimidines CIBA-GEIGY CORPORATION 1989-07-04 US claimed
US-4284770-A DEHALOGENATION, HYDRAZINE COMPOUND CIBA-GEIGY CORPORATION (US) 1981-08-18 US claimed