Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | FABP3 | P05413 | 7/20 | 0.48 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sebacic Acid SCHEMBL162436 | 0.96 | CA1 (0.55) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Pimelic Acid SCHEMBL29371853 | 0.96 | CA1 (0.55) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| SCHEMBL11609896 | 0.96 | CA1 (0.55) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Octanedioate SCHEMBL160025 | 0.96 | CA1 (0.55) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Azelaic Acid SCHEMBL162460 | 0.96 | CA1 (0.55) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL9820842 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL1194225 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL8006228 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL5146021 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL11050745 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117038170-A | Self-repairing cable with high temperature resistance and water blocking characteristics | 浙江万马股份有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-116425904-A | Supported Ziegler-Natta catalyst and preparation method and application thereof | 山东京博石油化工有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-114479269-A | Preparation method of polypropylene composite material, composite material and bumper | 浙江吉利控股集团有限公司 | 2022-05-13 | — | — | CN | claimed |
| EP-1069444-B1 | UV radiation system having materials for selectively attenuating radiation | JOHNSON & JOHNSON VISION CARE (US) | 2006-03-08 | — | — | EP | claimed |
| US-6465799-B1 | UV radiation system having materials for selectively attenuating radiation | JOHNSON & JOHNSON VISION CARE, INC. | 2002-10-15 | — | — | US | claimed |
| EP-1069444-A2 | UV radiation system having materials for selectively attenuating radiation | Johnson & Johnson Vision Care, Inc. (US) | 2001-01-17 | — | — | EP | claimed |
| EP-0478199-B1 | Polyvinyl chloride resin composition for powder molding | SUMITOMO CHEMICAL CO (JP) | 1997-06-25 | — | — | EP | claimed |
| EP-0416321-B1 | Crystalline polyolefin composition | CHISSO CORP (JP) | 1994-11-09 | — | — | EP | claimed |
| EP-0478199-A2 | Polyvinyl chloride resin composition for powder molding | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-04-01 | — | — | EP | claimed |
| US-5063264-A | Molding materials | CHISSO CORPORATION (JP) | 1991-11-05 | — | — | US | claimed |
| EP-0416321-A1 | Crystalline polyolefin composition | Chisso Corporation (JP) | 1991-03-13 | — | — | EP | claimed |
| US-4861816-A | Polyvinyl chloride resin composition for powder molding | SUMITOMO CHEMICAL COMPANY (JP) | 1989-08-29 | — | — | US | claimed |
| CN-110366597-B | Blood profiling with protease inhibitors | 善威生物私人有限公司 | 2024-03-29 | — | — | CN | disclosed |
| US-20240060997-A1 | Blood Preparation and Profiling | SANGUI BIO PTY LTD (AU) | 2024-02-22 | — | — | US | disclosed |
| CN-117038170-A | Self-repairing cable with high temperature resistance and water blocking characteristics | 浙江万马股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-116425904-A | Supported Ziegler-Natta catalyst and preparation method and application thereof | 山东京博石油化工有限公司 | 2023-07-14 | — | — | CN | disclosed |
| US-4861816-A | Polyvinyl chloride resin composition for powder molding | SUMITOMO CHEMICAL COMPANY (JP) | 1989-08-29 | — | — | US | disclosed |
| US-4136089-A | 2,2-DIETHYL-PROPANE-1,3-DIOL | BAYER AKTIENGESELLSCHAFT (DE) | 1979-01-23 | — | — | US | disclosed |
| US-4107149-A | Poly(ethylene/alkylene) terephthalates which crystallize rapidly | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-15 | — | — | US | disclosed |
| US-4086212-A | ESTERIFICATION OR TRANSESTERIFICATION | BAYER AKTIENGESELLSCHAFT (DT) | 1978-04-25 | — | — | US | disclosed |