Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12606620 | 1.00 | PLG (0.32) | PLGBACE1 | |
| SCHEMBL13685095 | 1.00 | PLG (0.32) | PLGBACE1 | |
| SCHEMBL13685232 | 1.00 | PLG (0.32) | PLGBACE1 | |
| SCHEMBL13685131 | 1.00 | PLG (0.32) | PLGBACE1 | |
| SCHEMBL13685239 | 1.00 | PLG (0.32) | PLGBACE1 | |
| SCHEMBL12606593 | 1.00 | PLG (0.32) | PLGBACE1 | |
| SCHEMBL8046136 | 0.89 | — | — | |
| SCHEMBL13685100 | 0.86 | F2 (0.33) | PLGBACE1 | |
| SCHEMBL12606619 | 0.85 | BACE1 (0.35) | BACE1 | |
| SCHEMBL13685160 | 0.85 | BACE1 (0.35) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592419-B2 | Macrocyclic inhibitors of hepatitis C virus NS3-serine protease | SCHERING CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |
| WO-2006113942-A2 | METHOD OF INHIBITING CATHEPSIN ACTIVITY | SCHERING CORPORATION (US) | 2006-10-26 | — | — | WO | disclosed |