Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 20/20 | 0.75 |
| ▸ | HTR2C | P28335 | 17/20 | 0.75 |
| ▸ | HTR2B | P41595 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL764996 | 0.90 | HTR2A (0.72) | HTR2AHTR2CHTR2B | |
| SCHEMBL764650 | 0.86 | HTR2A (1.00) | HTR2AHTR2C | |
| SCHEMBL763734 | 0.84 | HTR2C (0.85) | HTR2AHTR2CHTR2B | |
| SCHEMBL763546 | 0.82 | HTR2C (1.00) | HTR2AHTR2CHTR2B | |
| SCHEMBL764778 | 0.81 | MAPKAPK2 (0.70) | HTR2AHTR2C | |
| SCHEMBL764754 | 0.79 | HTR2C (0.77) | HTR2AHTR2CHTR2B | |
| SCHEMBL763595 | 0.79 | HTR2C (1.00) | HTR2AHTR2CHTR2B | |
| SCHEMBL764714 | 0.79 | MAPKAPK2 (0.72) | HTR2AHTR2C | |
| SCHEMBL14390104 | 0.79 | HTR2A (0.59) | HTR2AHTR2C | |
| SCHEMBL763670 | 0.79 | HTR2A (0.82) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871375-B1 | CARBOLINE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | PTC THERAPEUTICS INC (US) | 2012-02-29 | — | — | EP | disclosed |