⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10786787 | 0.80 | — | — | |
| SCHEMBL3633937 | 0.78 | — | — | |
| SCHEMBL127322 | 0.77 | — | — | |
| SCHEMBL16196002 | 0.77 | — | — | |
| SCHEMBL8402379 | 0.74 | — | — | |
| SCHEMBL11602571 | 0.74 | — | — | |
| SCHEMBL2409906 | 0.74 | — | — | |
| SCHEMBL344665 | 0.74 | — | — | |
| SCHEMBL10665150 | 0.74 | — | — | |
| SCHEMBL10671548 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024056498-A1 | OXINDOLE ALKALOID DERIVATIVES AS INHIBITORS OF SGLT2 | Société des Produits Nestlé S.A. (CH) | 2024-03-21 | — | — | WO | claimed |
| CN-105001222-A | New 8-(3-amino-piperidin-1-yl)-xanthine derivatives, preparing method and uses thereof as a pharmaceutic preparation | BOEHRINGER INGELHEIM PHARMA | 2015-10-28 | — | — | CN | claimed |
| US-20140309192-A1 | MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC, | 2014-10-16 | — | — | US | claimed |
| EP-2776407-A1 | MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2014-09-17 | — | — | EP | claimed |
| WO-2013070657-A1 | MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2013-05-16 | — | — | WO | claimed |
| CN-102964347-A | 8-[3-amino-piperidin-1-yl]-xanthines, the production thereof and the use of the same as medicaments | BOEHRINGER INGELHEIM PHARMA | 2013-03-13 | — | — | CN | claimed |
| US-7939548-B2 | Aminopyridines, e.g.,N-{[6-(aminomethyl)(2-pyridyl)]methyl}(2-{[2-(3-fluorophenyl)ethyl]amino}-5-(3-pyridyl)(3-pyridyl))carboxamide; smooth muscle myosin or non-muscle myosin modulator; hypotensive agent; asthma, COPD, bronchoconstrictive disease, glaucoma, pre-menstrual cramps, erectile dysfunction | CYTOKINETICS, INC. (US) | 2011-05-10 | — | — | US | claimed |
| US-7932270-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2011-04-26 | — | — | US | claimed |
| US-7868022-B2 | 2-amino-quinoline derivatives useful as inhibitors of β-secretase (BACE) | JANSSEN PHARMACEUTICA NV (BE) | 2011-01-11 | — | — | US | claimed |
| CN-100577658-C | Quinazoline derivatives | ASTRAZENECA AB | 2010-01-06 | — | — | CN | claimed |
| US-20080132545-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. | 2008-06-05 | — | — | US | claimed |
| WO-2008016643-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-02-07 | — | — | WO | claimed |
| WO-2007092854-A2 | 2-AMINO-QUINOLINE DERIVATIVES USEFUL AS INHIBITORS OF β-SECRETASE (BACE) | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-08-16 | — | — | WO | claimed |
| WO-2007042500-A1 | BORATE SALTS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF | CHEMETALL GMBH (DE) | 2007-04-19 | — | — | WO | claimed |
| US-20070043010-A1 | Quinazoline derivatives | ASTRAZENECA UK LIMITED (GB) | 2007-02-22 | — | — | US | claimed |
| CN-1886399-A | Quinazoline derivatives | ASTRAZENECA AB (SE) | 2006-12-27 | — | — | CN | claimed |
| CN-1675212-A | 8- [ 3-amino-piperidin-1-yl ] -xanthines, process for their preparation and their use as pharmaceutical preparations | BOEHRINGER INGELHEIM PHARMA (DE) | 2005-09-28 | — | — | CN | claimed |
| CN-1041724-C | 2-arylaminopyrimidinone derivative, and herbicide and plant growth regulator using the same | NISSAN CHEMICAL IND LTD (JP) | 1999-01-20 | — | — | CN | claimed |
| CN-1198742-A | Pyrimidin-4-one derivatives, their use as herbicides, intermediates for their production and process for producing these compounds | SUMITOMO CHEMICAL CO (JP) | 1998-11-11 | — | — | CN | claimed |
| CN-1079736-A | 2-arylamino-pyrimidine ketone derivatives, and the weedkiller and the plant-growth regulator of this component of use | NISSAN CHEMICAL IND LTD (JP) | 1993-12-22 | — | — | CN | claimed |