Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | TLR2 | O60603 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22214463 | 0.98 | MEN1 (0.44) | MEN1KMT2ASMN1; SMN2CA2TSHR | |
| SCHEMBL752059 | 0.84 | EPHX2 (0.44) | MEN1KMT2ASMN1; SMN2CA2TSHR | |
| SCHEMBL17915501 | 0.82 | MEN1 (0.44) | MEN1KMT2ASMN1; SMN2CA2TSHR | |
| SCHEMBL19607890 | 0.82 | TSHR (0.44) | MEN1KMT2ASMN1; SMN2CA2TSHR | |
| SCHEMBL16303444 | 0.82 | TSHR (0.44) | MEN1KMT2ASMN1; SMN2CA2TSHR | |
| SCHEMBL16096657 | 0.82 | SMN1; SMN2 (0.39) | MEN1KMT2ASMN1; SMN2CA2TSHR | |
| SCHEMBL14274645 | 0.82 | MEN1 (0.52) | MEN1KMT2ASMN1; SMN2TSHRMTNR1A | |
| SCHEMBL16303438 | 0.81 | MEN1 (0.35) | MEN1KMT2ACA2TSHRMTNR1A | |
| SCHEMBL16303480 | 0.81 | MEN1 (0.39) | MEN1KMT2ASMN1; SMN2CA2TSHR | |
| SCHEMBL25779299 | 0.81 | MEN1 (0.39) | MEN1KMT2ASMN1; SMN2CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014200682-A1 | BIDENTATE-BINDING MODULATORS OF LRRK2 AND JNK KINASES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2014-12-18 | — | — | WO | disclosed |