Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 16/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.49 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15029434 | 0.89 | PIK3CB (0.67) | PIK3CBPIK3CAPIK3CDPIK3R1 | |
| SCHEMBL9950973 | 0.86 | PIK3CB (0.67) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL9950975 | 0.86 | PIK3CB (0.67) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL15029325 | 0.84 | PIK3CB (0.52) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL15029966 | 0.81 | PIK3CB (0.63) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL15009172 | 0.81 | PIK3CB (0.63) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL15030047 | 0.81 | PIK3CB (0.63) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL15029624 | 0.81 | PIK3CB (0.63) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL15029343 | 0.78 | PIK3CB (0.51) | PIK3CBPIK3CAPIK3CDPIK3R1 | |
| SCHEMBL15029433 | 0.78 | PIK3CB (0.60) | PIK3CBPIK3CAPIK3CDPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8912180-B2 | Heterocyclic compound | ASTELLAS PHARMA INC. (JP) | 2014-12-16 | — | — | US | disclosed |