⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19937250 | 0.63 | — | — | |
| SCHEMBL557391 | 0.62 | — | — | |
| SCHEMBL4058581 | 0.60 | — | — | |
| SCHEMBL13083560 | 0.57 | — | — | |
| SCHEMBL12189982 | 0.56 | — | — | |
| SCHEMBL17104883 | 0.56 | — | — | |
| SCHEMBL19752901 | 0.56 | — | — | |
| SCHEMBL19464247 | 0.55 | — | — | |
| SCHEMBL14138851 | 0.54 | — | — | |
| SCHEMBL9048349 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932251-B2 | 6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives | N.V. ORGANON (NL) | 2011-04-26 | — | — | US | disclosed |
| EP-2178873-B1 | 6-PHENYL-1H-IMIDAZO[4,5-C]PYRIDINE-4-CARBONITRILE DERIVATIVES AS CATHEPSIN INHIBITORS | ORGANON NV (NL) | 2010-12-22 | — | — | EP | disclosed |
| EP-2178873-A1 | 6-PHENYL-1H-IMIDAZO[4,5-C]PYRIDINE-4-CARBONITRILE DERIVATIVES AS CATHEPSIN INHIBITORS | N.V. Organon (NL) | 2010-04-28 | — | — | EP | disclosed |
| US-20090099172-A1 | 6-PHENYL-1H-IMIDAZO[4,5-c]PYRIDINE-4-CARBONITRILE DERIVATIVES | N. V. ORGANON | 2009-04-16 | — | — | US | disclosed |
| WO-2009010491-A1 | 6-PHENYL-1H-IMIDAZO[4,5-C]PYRIDINE-4-CARBONITRILE DERIVATIVES AS CATHEPSIN INHIBITORS | N.V. ORGANON (NL) | 2009-01-22 | — | — | WO | disclosed |