Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 19/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 15/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 13/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 10/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16308426 | 0.95 | PIK3CB (0.50) | PIK3CBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL16308522 | 0.94 | PIK3CB (0.50) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL16308468 | 0.91 | PIK3CB (0.51) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL16308425 | 0.91 | PIK3CB (0.58) | PIK3CBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL16308427 | 0.89 | PIK3CB (0.57) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL16308521 | 0.89 | PIK3CB (0.54) | PIK3CBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL15009836 | 0.89 | PIK3CB (0.54) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL15029914 | 0.88 | PIK3CB (0.56) | PIK3CBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL16308429 | 0.88 | PIK3CB (0.54) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL16308540 | 0.88 | PIK3CB (0.57) | PIK3CBPIK3CDPIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8912180-B2 | Heterocyclic compound | ASTELLAS PHARMA INC. (JP) | 2014-12-16 | — | — | US | disclosed |
| US-8912180-B2 | Heterocyclic compound | ASTELLAS PHARMA INC. (JP) | 2014-12-16 | — | — | US | disclosed |