⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21566959 | 0.80 | TSHR (0.35) | — | |
| SCHEMBL289826 | 0.76 | — | — | |
| SCHEMBL996119 | 0.76 | — | — | |
| SCHEMBL13765285 | 0.74 | — | — | |
| SCHEMBL212208 | 0.71 | — | — | |
| SCHEMBL665258 | 0.71 | TSHR (0.45) | — | |
| SCHEMBL14404817 | 0.70 | TSHR (0.39) | — | |
| SCHEMBL19051109 | 0.70 | — | — | |
| SCHEMBL20321513 | 0.70 | HDAC3 (0.37) | — | |
| Hydrochloric Acid SCHEMBL6646249 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10189838-B2 | Aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection | HOFFMAN-LA ROCHE INC. (US) | 2019-01-29 | — | — | US | disclosed |
| US-20180072726-A9 | NOVEL AZA-OXO-INDOLES FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2018-03-15 | — | — | US | disclosed |
| EP-2611299-A1 | PESTICIDAL COMPOSITIONS | Dow AgroSciences LLC (US) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012030681-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-03-08 | — | — | WO | disclosed |