Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16309496 | 0.92 | GRM5 (0.61) | GRM5 | |
| SCHEMBL16309449 | 0.92 | GRM5 (0.61) | GRM5 | |
| SCHEMBL16309462 | 0.91 | GRM5 (0.63) | GRM5 | |
| SCHEMBL16704503 | 0.90 | GRM5 (0.53) | GRM5 | |
| SCHEMBL16309428 | 0.90 | GRM5 (0.53) | GRM5 | |
| SCHEMBL16704469 | 0.89 | GRM5 (0.59) | GRM5 | |
| SCHEMBL16295319 | 0.89 | GRM5 (0.70) | GRM5 | |
| SCHEMBL16309480 | 0.89 | GRM5 (0.62) | GRM5 | |
| SCHEMBL16309492 | 0.88 | GRM5 (0.70) | GRM5 | |
| SCHEMBL16704534 | 0.87 | GRM5 (0.51) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013192346-A9 | SUBSTITUTED BICYCLIC ALKOXY PYRAZOLE ANALOGS AS ALLOSTERIC MODULATORS OF MGLUR5 RECEPTORS | VANDERBILT UNIVERSITY (US) | 2014-12-18 | — | — | WO | disclosed |