Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 4/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.41 |
| ▸ | TUBB | P07437 | 4/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16311812 | 0.85 | MAPK10 (0.44) | FYNTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16311791 | 0.85 | FYN (0.46) | PDGFRBPDGFRAFYNTUBB4ATUBB | |
| SCHEMBL16306439 | 0.83 | FYN (0.34) | PDGFRBPDGFRAFYNKITFPR2 | |
| SCHEMBL16311834 | 0.82 | MAPK10 (0.46) | PDGFRBPDGFRAFYNTUBB4ATUBB | |
| SCHEMBL19890354 | 0.81 | FYN (0.48) | PDGFRBPDGFRAFYNPDE4BKIT | |
| SCHEMBL16290837 | 0.81 | PDGFRB (0.43) | PDGFRBPDGFRAFYNTUBB4ATUBB | |
| SCHEMBL16296759 | 0.80 | FYN (0.47) | PDGFRBPDGFRAFYNTUBB4ATUBB | |
| SCHEMBL17752371 | 0.77 | PDGFRB (0.46) | PDGFRBPDGFRAFYNTUBB4ATUBB | |
| SCHEMBL24017210 | 0.75 | FYN (0.56) | PDGFRBPDGFRAFYNTUBB4ATUBB | |
| SCHEMBL15624567 | 0.75 | CYP1A1 (0.58) | PDGFRBPDGFRAFYNPDE4BKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014201173-A1 | BICYCLIC SULFONAMIDE COMPOUNDS AS SODIUM CHANNEL INHIBITORS | AMGEN INC. (US) | 2014-12-18 | — | — | WO | disclosed |