Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4538499 | 0.89 | GRM5 (0.70) | GRM5 | |
| SCHEMBL13585308 | 0.88 | GRM5 (0.71) | GRM5 | |
| SCHEMBL4542307 | 0.88 | GRM5 (0.71) | GRM5 | |
| SCHEMBL13585625 | 0.87 | GRM5 (0.70) | GRM5 | |
| SCHEMBL13585464 | 0.86 | GRM5 (0.80) | GRM5 | |
| SCHEMBL13585666 | 0.86 | GRM5 (0.68) | GRM5 | |
| SCHEMBL4560151 | 0.83 | GRM5 (0.91) | GRM5 | |
| SCHEMBL13584726 | 0.83 | GRM5 (0.82) | GRM5 | |
| SCHEMBL4560730 | 0.82 | GRM5 (0.77) | GRM5 | |
| SCHEMBL13640323 | 0.82 | GRM5 (0.77) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638022-B1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | BRISTOL MYERS SQUIBB CO (US) | 2014-12-24 | — | — | EP | disclosed |